14 results
Pulmonary Renal Syndrome

Definition: Diffuse alveolar hemorrhage + Glomerulonephritis
Presentation (Pulmonary and renal manifestations can occur weeks apart):
Pulmonary Renal ... Diagnosis for Pulmonary ... high resolution chest ... Bronchoscopy with serial ... #differential #
The fourth pattern includes abnormalities that result in decreased lung attenuation or air-filled lesions.
These include:
- Emphysema
-
Honeycombing Most diseases ... #Diagnosis #Radiology ... #Pulmonary #CTChest ... LowAttenuation #Differential ... #Diagram #Comparison
Pulmonary Renal Syndromes - OnePager Summary
Autoimmune ANCA vasculitis (AAV): GPA (granulomatous with polyangiitis), EGPA (eosinophilic granulomatosis
Pulmonary Renal ... Autoimmune ANCA vasculitis ... mononeuritis multiplex WORKUP ... confirm DAH, r/o infection ... • IF staining patterns
Miliary Pattern - Chest Radiology
 • Miliary opacities are scattered, small (1 -4 mm) nodules
 •
Miliary Pattern ... hematogenous spread of a disease ... Endemic fungi: Histo ... thyroid, melanoma, renal ... diagnosis #pulmonary
Clinical Classification of Pulmonary Hypertension

1. Pulmonary arterial hypertension from pulmonary vasculopathy
Idiopathic pulmonary arterial hypertension
Heritable gene mutations
- HIV infection ... and obstructive pattern ... mediastinitis, chronic renal ... Classification #Diagnosis ... #Differential #
On the left some diseases with a nodular pattern.
1. Hypersensitivity pneumonitis: ill defined centrilobular nodules.
2. Miliary
the left some diseases ... #Radiology #Pulmonary ... #CTChest #Nodular ... #Differential # ... Comparison #Table
Vasculitis and Vasculitides - Differential Diagnosis Framework

When to Consider Vasculitis:
 • Purpura, ischemic skin lesions
 •
progressing GN • New pulmonary ... and renal abnormalities ... + MPO-ANCA MEDIUM ... to exclude are infections ... differential #diagnosis
Pulmonary Infections in HIV-AIDS
Bacterial: 
 • No organism identified, Strep pneumoniae, H. influenzae, S.aureus, Streptococcus Grp
Pulmonary Infections ... Cryptococcal Ag, Urine Histo ... Diseases Fellows ... #workup #diagnosis ... #evaluation #differential
Vasculitis - Differential Diagnosis Framework

When to Consider Vasculitis:
• Purpura, ischemic skin lesions
• Mononeuritis multiplex
• Hematuria, proteinuria,
Vasculitis - Differential ... and renal abnormalities ... Vasculitis Differential ... primary condition MEDIUM ... #Differential #Diagnosis
Approach to Eosinophilic Lung Diseases
 • Acute Eosinophilic Pneumonia (< 1 wk) - ~30yo, M; Recent
arthralgias, CV, renal ... , CNS, skin • Infectious ... #pulmonary #differential ... #diagnosis #comparison ... #table #eosinophilia