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diagnosis differential leukemia management anemia aplastic autoimmune chronic cll comparison gammopathy hodgkins lymphocytic lymphoma mds mgus monoclonal myelitis myelodysplasia myelodysplastic
Autoimmune Myositis Necrotizing myopathy is associated with higher CK levels, greater level of muscle weakness, less systemic
levels, greater level ... less systemic symptoms ... heliotrope rash, Shaw sign ... , holster sign, ... continue to have significant
Hodgkin's Lymphoma vs Non-Hodgkin's Lymphoma - Comparison Hodgkin's Lymphoma: • Epidemiology: young adults 20-30, older 50-70 •
adults 20-30, older ... - B symptoms ... Lymphomas • Other hematologic ... NonHodgkins #comparison #oncology ... #differential #hematology
Monoclonal Gammopathy of Undetermined Significance (MGUS) - Summary Framework Hematologic disorder characterized by the presence of either
of Undetermined Significance ... patients 50 years or older ... constitutional symptoms ... #Undetermined #Significance ... #oncology
Leukemias Overview: ALL, CML, AML, APML, CLL Acute leukemias > 20% blasts in the peripheral blood smear
Headaches, bone pain, fever ... • Auer Rods Significant ... translocation • Significant ... #Leukemia #Hematology ... #Oncology #Diagnosis
Aplastic Anemia - Overview Who? • M = F • 3 peaks: 1) Childhood 2) 15-25 years 3) >60 years What? • Aplastic anemia
Marrow (Toxic injury ... index < 2 • EPO Level ... • Improve the symptoms ... Aplastic #Anemia #oncology ... #hematology #diagnosis
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
Affects mainly older ... with no early symptoms ... Physical Exam/Signs ... diagnosis #workup #oncology ... #hematology
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
100,000 people older ... age 70 years Symptoms ... of Undetermined Significance ... Syndromes #diagnosis #hematology ... #oncology
Transverse Myelitis Overview Focal inflammatory disorder of the spinal cord resulting in rapid onset of weakness, sensory
Presentation: Injury ... back pain at/near level ... • Bilateral signs ... and/or symptoms ... defined sensory level
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