23 results
Sarcoidosis - Diagnosis and Management Summary
Epidemiology
1) High incidence in Scandinavian countries (11-24 cases per 100,000 individuals
Diagnosis and Management ... tissue: Epithelioid cells ... symptoms are not caused ... anterior/posterior MSK ... #Signs #Symptoms
Hemophagocytic Lymphohistiocytosis (HLH)
Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
• Clinical: fever ... , ↓ Fibrinogen level ... Drugs, Unknown cause ... Lymphohistiocytosis #diagnosis #management ... treatment #summary #rheumatology
Polycythemia - Differential Diagnosis Algorithm
Polycythemia itself isn’t a diagnosis. Like many things, it is a condition
an underlying cause ... Too many cells in ... Better call hematology ... about secondary causes ... Algorithm #workup #hematology
Aplastic Anemia - Overview

Who?
• M = F
• 3 peaks:	1) Childhood	2) 15-25 years	3) >60 years

What?
• Aplastic anemia
Presentation: • Fever ... and petechiae Causes ... index < 2 • EPO Level ... Anemia #oncology #hematology ... #diagnosis #management
Leukostasis vs Tumor Lysis Syndrome
Leukostasis:
 • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
high WBC count cause ... - 80% have fever ... WBC >100k, + lab signs ... TLS #diagnosis #management ... #hematology
IDSA Algorithm for the Management of Purulent skin and soft tissue infections (SSTIs). 
Mild infection: for
Algorithm for the Management ... 12 000 or <400 cells ... erysipelas with no focus ... including those caused ... SSTIs #Algorithm #Management
Hepatopulmonary Syndrome - Diagnosis and Management Summary
A defect in arterial oxygenation due to a gas exchange
Diagnosis and Management ... lung disease Caused ... patients aged 65 and older ... SpO2 > 88% • Management ... #treatment #hepatology
Post-Transplantation Lymphoproliferative Disorders (PTLD)
Definition: Lymphoid and/or plasmacytic proliferations that occur as a result of immunosuppression in
in lung>heart>liver ... symptoms, unexplained hematologic ... EBV viral load, signs ... to 50% of PTLD cases ... oncology #diagnosis #management
Transverse Myelitis Overview

Focal inflammatory disorder of the spinal cord resulting in rapid onset of weakness, sensory
back pain at/near level ... • Bilateral signs ... defined sensory level ... Pleocytosis > 100 cells ... Myelitis #diagnosis #management
Disseminated Intravascular Coagulation (DIC) Overview

Increased Clotting and Consumption of Clotting Factors

Findings:
 • Bleeding
 • Recent history
Schistocytes, helmet cells ... DIC • Severe Liver ... Treat primary cause ... #treatment #management ... #hematology