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Algorithm for treatment of Diabetic Ketoacidosis (DKA) and Hyperglycemic Hyperosmolar State (HHS)

#DKA #HHS #Algorithm #Diabetic #Ketoacidosis
Ketoacidosis (DKA ... ) and Hyperglycemic ... State (HHS) #DKA ... #Ketoacidosis #Hyperglycemic
Ketosis Disorders - Comparison Table
 • Starvation Ketosis
 • Alcoholic Ketoacidosis (AKA)
 • Diabetic Ketoacidosis (DKA)
Ketoacidosis (AKA ... Ketoacidosis (DKA ... • Euglycemic DKA ... • Hyperglycemic ... State (HHS) • DKA
DKA vs HHS
 - Think of DKA and HHS on a spectrum of hyperglycemic emergencies
 -
DKA vs HHS - Think ... of DKA and HHS ... a spectrum of hyperglycemic ... look like overlap DKA ... #hyperosmolar #hyperglycemic
Guideline for management of adult patients with diabetic ketoacidosis (DKA) or hyperosmolar hyperglycemic state (HHS)

UCSD Internal
ketoacidosis (DKA ... or hyperosmolar hyperglycemic ... Medicine @ucsdim #DKA
Hyperglycemic Crisis - Algorithm for DKA/HHS

Diagnostic criteria for DKA:
 • pH < 7.3
 • Anion gap
Hyperglycemic Crisis ... Algorithm for DKA ... Diagnostic criteria for DKA ... MatthewHoMD #DKA ... #HHS #Hyperglycemic
Pathophysiology of Diabetic Ketoacidosis (DKA) and Hyperglycemic Hyperosmolar Syndrome (HHS)
Absolute Insulin deficit:
 - Type I DM:
Ketoacidosis (DKA ... ) and Hyperglycemic ... Polydipsia #dka ... #ketoacidosis #hyperglycemic
Pathyophysiology - hyperglycemic crises in patients with diabetes 
Key signs/symptoms of HHS/DKA:
Both: Polyuria, polydipsia, weight loss,
Pathyophysiology - hyperglycemic ... symptoms of HHS/DKA ... , hypotension) DKA ... #EM #IM #Endo #DKA
Ketosis Disorders
Ketone bodies are a normal metabolic energy source. Excessive unregulated production of ketones, often accompanied
ketoacidosis (DKA ... • Euglycemic DKA ... • Hyperglycemic ... • DKA/HHS Overlap ... features of both DKA
Secondary Causes of Hypothermia - Differential Diagnosis Framework

Definition:
- Core temp < 35°C

Infectious:
 - Sepsis

Neuromuscular Disease:
 -
deficiency - Hypoglycemia ... Endocrine: - DKA ... Hypothyroidism - Hypoglycemia
There are similarities and differences between these 3 conditions which all carry treatment implications. Each mimic
also present with Hypoglycemia ... If Hyperglycemic ... you risk causing Hypoglycemia ... DKA is essentially