46 results
Drugs and Classes Associated with DILI and Type of Liver Injury

#Medications #Differential #DrugInduced #LiverInjury #Hepatology #Pharmacology
Drugs and Classes ... Associated with DILI ... Type of Liver Injury ... #Medications ... #Differential #
Diagnosis and Management of Idiosyncratic Drug-induced Liver Injury (DILI)

DILI Types:
 • Intrinsic - predictable, dose dependent
Diagnosis and Management ... Idiosyncratic Drug-induced ... Liver Injury (DILI ... #Drug #induced ... Idiosyncratic #differential
Drug Induced Liver Injury (DILI) - Stepwise Diagnosis Algorithm
DILI suspicion
Features toxic aetiology: Skin involvement, Kidney injury,
Drug Induced Liver ... Injury (DILI) - ... Stepwise Diagnosis ... information (e.g. dose ... duration), Several medications
Drugs Commonly Implicated as Triggers of Drug Induced Thrombocytopenia
#Diagnosis #Hematology #Thrombocytopenia #Differential #DrugInduced #Medications
as Triggers of Drug ... Induced Thrombocytopenia ... #Diagnosis #Hematology ... Thrombocytopenia #Differential ... #DrugInduced #Medications
Stress Dose Steroids - Indications and Dosing

SUPPRESSED HPA AXIS:
 prednisone >20mg/day x 3 weeks or more
Stress Dose Steroids ... - Indications and ... StressDose #Steroids #Indications ... #Dosing #Endocrinology ... #Diagnosis #Management
Drug Induced Kidney Injury
 • Pre-Renal: NSAIDS, CNI, ACEI/ARB, IL-2 therapy, Diuretics CAR-T therapy
 • Osmotic
Drug Induced Kidney ... induced vasculitis ... #KidneyInjury #differential ... #diagnosis #algorithm ... #nephrology #Medications
Acute Kidney Injury (AKI) - Differential Diagnosis Framework

PRE-Renal AKI:
 • Hypovolemia
 • Congestion
 • Medications
 •
Acute Kidney Injury ... (AKI) - Differential ... Diagnosis Framework ... Congestion • Medications ... Infection-mediated, Drug-induced
Drug-Induced Thrombocytopenia
The diagnosis of drug-induced thrombocytopenia can be made only by demonstrating resolution of thrombocytopenia once
Drug-Induced Thrombocytopenia ... drug-induced thrombocytopenia ... patients with drug-induced ... Thrombocytopenia #Differential ... #DrugInduced #Medications
Elevated Liver Function Tests (LFTs) - Differential Diagnosis Framework
Mild (<100-500): 
 • NAFLD
 • Cirrhosis
 •
Tests (LFTs) - Differential ... Diagnosis Framework ... (>1000): • DILI ... (Drug-induced liver ... injury) • Ischemic
DPP4 Inhibitors - Normal and Renal Dosing

Increase Incretins (GLP-I & GIP) -> Stimulates Insulin, Inhibits Glucagon
Normal and Renal Dosing ... thing about this drug ... different than other medications ... This drug class ... Diabetes #DM2 #Endocrinology