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diagnosis hematology hemophagocytic lymphohistiocytosis behcet disease gbs guillain hemeonc leukostasis lysis neurology rheumatology tls treatment tumor
Hemophagocytic Lymphohistiocytosis (HLH) Definition: Overwhelming clinical syndrome associated with excessive macrophage activation and cytokine storm due to
Overwhelming clinical syndrome ... signs and symptoms ... can mimic common infections ... Treatment: • Infection ... Lymphohistiocytosis #diagnosis #management
Guillain-Barré Syndrome (GBS) Acute autoimmune demyelinating polyradiculoneuropathy that presents with rapidly progressive flaccid weakness Epidemiology: • Incidence: 1
Guillain-Barré Syndrome ... than one after symptom ... the underlying pathophysiology ... #Syndrome #diagnosis ... #management #neurology
Leukostasis vs Tumor Lysis Syndrome Leukostasis: • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
Leukostasis: • Pathophysiology ... ischemia, bowel infarction ... WBC >100k, + lab signs ... : • Pathophysiology ... TLS #diagnosis #management
Behçet's Syndrome Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy Epidemiology: • Young
common in Asia • HLA-B51 ... +/- myocardial infarction ... inhibitors • Uveitis- Ophthalmology ... #diagnosis #management ... #signs #symptoms
Hemophagocytic Lymphohistiocytosis (HLH) High mortality without prompt recognition and management. HLH is a critical diagnostic consideration in
Triggers: ▪ Infections ... Presentation • Common Signs ... and Symptoms: ... Pathophysiology ... underlying trigger: Infections
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