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diagnosis differential management chronic cll infectiousdiseases leukemia lymphocytic aids algorithm causes classification diffuse erythematosus hemeonc hemophagocytic hiv hlh lad lung
Causes of Diffuse Lymphadenopathy - Differential Diagnosis Algorithm Reactive: - Systemic Inflammatory •
Pseudotumor - Infectious ... History of Bleeding, Infection ... Lymphocytic Leukemia (CBC ... Algorithm #Causes #Hematology ... #Oncology
Hemophagocytic Lymphohistiocytosis (HLH) Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
Triggering factor (infection ... →Activation of CD8 ... salmonella, ...), Parasites ... Still disease, Infection ... treatment #summary #rheumatology
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
weeks without infection ... Lymphocytosis on CBC ... surface molecules: CD5 ... diagnosis #workup #oncology ... #hematology
Chronic Lymphocytic Leukemia (CLL) - Summary Overview: • Most common leukemia in adults • Disorder of
Vmphocytosis on routine CBC ... Complications: 1) Infection ... Lymphocytic #Leukemia #oncology ... #hematology #hemeonc
Lung Infections in HIV - Differential Diagnosis Framework Disease by CD4 Count: Any CD4 Count: • Mycobacterium tuberculosis,
Lung Infections ... possible in HIV PARASITIC ... Microsporidium #Lung #Infections ... #HIV #AIDS #pulmonary ... differential #diagnosis #infectiousdiseases
Nontuberculous Mycobacteria (NTM) Infections Mycobacterial species other than those belonging to the Mycobacterium tuberculosis complex and
Illnesses: • Pulmonary ... complicate MAC pulmonary ... Advanced HIV (CD4 ... Hematologic malignancy ... differential #diagnosis #infectiousdiseases
Sjogren's Syndrome Overview Epidemiology: • F > M: 9:1 • 5-6th Decades (can be any age) Autoimmune exocrinopathy multisystemic disease
/aggregate) of CD4 ... Disease: • 10%-15% Pulmonary ... , INC risk PE, Pulmonary ... Nephrogenic DI Hematologic ... Sjogrens #Syndrome #Rheumatology
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
Non-autoimmune rheumatologic ... fibromyalgia) • Infections ... Vasculitis: • Distal ... titers > 1:80 • CBC ... Erythematosus #Diagnosis #Rheumatology
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
progressing GN • New pulmonary ... glomerulonephritis and/or pulmonary ... to exclude are infections ... Lab Tests: • CBC ... differential #diagnosis #rheumatology
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