13 results
CNS Infection in HIV / AIDS - Differential Diagnosis Framework

Principles of HIV-Associated CNS Opportunistic Infections:
 •
Antimicrobial treatment ... change, seizures, visual ... gait ataxia, and visual ... Headache, vomiting, visual ... opportunistic #InfectiousDiseases
Hemophagocytic Lymphohistiocytosis (HLH)
Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
→Activation of CD8 ... salmonella, ...), Parasites ... Unknown cause Treatment ... diagnosis #management #treatment ... #summary #rheumatology
Chronic Lymphocytic Leukemia - Summary

Cancer affecting lymphocytes/Mature B cell neoplasm
 • Lymphocytes accumulate in large numbers
weeks without infection ... Lymphocytosis on CBC ... surface molecules: CD5 ... microglobulin Treatment ... workup #oncology #hematology
Immune Reconstitution Inflammatory Syndrome - Overview of IRIS

What Is IRIS?
	• A state of hyperinflammatory response that
Reconstitution Inflammatory Syndrome ... six months of treatment ... ART ↑ improves CD4 ... PML), Confusion, visual ... #Inflammatory #Syndrome
Sweet Syndrome

Acute febrile neutrophilic dermatosis (Sweets Syndrome) is a skin condition characterized by fever and inflamed
, breast CA - Hematologic ... Upper respiratory infection ... gastrointestinal infection ... - CBC may also ... Treatment: - Systemic
Lung Infections in HIV - Differential Diagnosis Framework

Disease by CD4 Count:
Any CD4 Count:
 • Mycobacterium tuberculosis,
Lung Infections ... Pneumonia: • 3 syndromes ... of a "flu-like syndrome ... possible in HIV PARASITIC ... differential #diagnosis #infectiousdiseases
Nontuberculous Mycobacteria (NTM) Infections 

Mycobacterial species other than those belonging to the Mycobacterium tuberculosis complex and
: • Syndrome of ... Advanced HIV (CD4 ... Hematologic malignancy ... diagnosis • Microbiologic ... differential #diagnosis #infectiousdiseases
Pulmonary Renal Syndromes - OnePager Summary
Autoimmune ANCA vasculitis (AAV): GPA (granulomatous with polyangiitis), EGPA (eosinophilic granulomatosis
Pulmonary Renal Syndromes ... Cardiac (in EGPA) • Digital ... coagulopathy) • CBC ... confirm DAH, r/o infection ... diagnosis #management #treatment
Sjogren's Syndrome Overview

Epidemiology:
• F > M: 9:1
• 5-6th Decades (can be any age)

Autoimmune exocrinopathy multisystemic disease
Sjogren's Syndrome ... /aggregate) of CD4 ... Interstitial nephritis • Distal ... Nephrogenic DI Hematologic ... Adenocarcinoma Treatment
SLE (Systemic Lupus Erythematosus)

Suspect:
Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
fibromyalgia) • Infections ... Malignancy (e.g. hematologic ... vein thrombosis Hematologic ... Vasculitis: • Distal ... titers > 1:80 • CBC