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diagnosis hemophagocytic lymphohistiocytosis product reactions treatment bloodstream catheter causes classification crbsi dermatology differential hemeonc hodgkins lymphoma oncology petechiae petechial physicalexam
Hemophagocytic Lymphohistiocytosis (HLH) Definition: Overwhelming clinical syndrome associated with excessive macrophage activation and cytokine storm due to
can mimic common infections ... acute or subacute febrile ... following: • Fever ... Lymphohistiocytosis #diagnosis #management ... #treatment #hematology
Hemophagocytic Lymphohistiocytosis (HLH) Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
Phagocytosis of blood ... • Clinical: fever ... : • Infections ... Lymphohistiocytosis #diagnosis #management ... treatment #summary #rheumatology
Causes of Petechial Rash - Differential Diagnosis Algorithm Pinpoint areas (less than 2 mm) of hemorrhage, which
Differential Diagnosis Algorithm ... Red Flags: • Fever ... medication Febrile ... : • Complete blood ... • Fecal occult blood
Suspected catheter-related bloodstream infection - Management Algorithm • Temperature 37.8 C • Rigors
- Management Algorithm ... purulence Obtain blood ... • Persistent fever ... • Persistent fever ... #Management #Algorithm
Blood Transfusion Reactions Immune Mediated: • Febrile Non-Hemolytic Transfusion Reaction (FNHTR): Most common immune reaction to transfusion.
Mediated: • Febrile ... S/sx: Fever, flank ... have drop in Hct, fever ... Sx include: fever ... #hematology #reactions
Blood Product Transfusions One Pager Summary Type and screen - determines blood type and detects in recipient
Mediated: - Febrile ... S/sx: Fever, flank ... have drop in Hct, fever ... Sx include: fever ... #hematology #reactions
Hemophagocytic Lymphohistiocytosis (HLH) High mortality without prompt recognition and management. HLH is a critical diagnostic consideration in
consideration in febrile ... Characteristics: Persistent fever ... Persistent high fever ... Fever b. ... #Hematology #HemeOnc
Hodgkin's Lymphoma Overview Hodgkin's lymphoma (HL) is an uncommon hematological malignancy arising from mature B cells. It
History of EBV infection ... • Dyspnea • Fever ... Workup: • Full Blood ... classification #hematology ... #oncology #management
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