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diagnosis anemia aplastic febrile hemophagocytic infant lp lymphohistiocytosis oncology pediatrics peds rheumatology risk stepbystep stratification activation bacilliformis bartonella bloodstream catheter
Suspected catheter-related bloodstream infection - Management Algorithm • Temperature 37.8 C • Rigors
Antibiotic Management ... • Persistent fever ... complicated CRBSI: • Severe ... • Persistent fever ... Hernodynamically stable after treatment
Hemophagocytic Lymphohistiocytosis (HLH) Definition: Overwhelming clinical syndrome associated with excessive macrophage activation and cytokine storm due to
following: • Fever ... • Bicytopenia Treatment ... rapidly, and empiric antibiotic ... Lymphohistiocytosis #diagnosis #management ... #treatment #hematology
Aplastic Anemia - Illness Script Signs and symptoms: • Recurrent infections from neutropenia • Mucosal bleeding from
megaloblastic anemia Treatment ... (transfusions, antibiotics ... if neutropenic fever ... Anemia #diagnosis #management ... #treatment #hematology
Macrophage Activation Syndrome (MAS) Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH) What? A subset of
disease • Periodic fever ... multiorgan failure • Fever ... - Nonremitting fever ... Treatment: • Corticosteroids ... #Hematology #Rheumatology
Oroya Fever Hematologic disease caused by Bartonella bacilliformis Restricted to the Andes highlands of Peru & Ecuador B. bacilliformis:
Oroya Fever Hematologic ... Inflammation: high fever ... • RBC lysis → severe ... TREATMENT: ​• Acute ... gabrieltalledop #Oroya #Fever
Hemophagocytic Lymphohistiocytosis (HLH) Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
• Clinical: fever ... Unknown cause Treatment ... Lymphohistiocytosis #diagnosis #management ... #treatment #summary ... #rheumatology
“Step by Step” – the new kid on the block – aims to risk stratify this
investigations and treatments ... an infant with fever ... #Diagnosis #Management ... #LP #Antibiotics ... Stratification #Fever
The Febrile Infant Step-by-Step Algorithm This is an algorithm developed by European emergency physicians to identify low-risk
puncture nor empiric antibiotic ... treatment. http ... Diagnosis #EBM #Management ... #LP #Antibiotics ... Stratification #Fever
Aplastic Anemia - Overview Who? • M = F • 3 peaks: 1) Childhood 2) 15-25 years 3) >60 years What? • Aplastic anemia
Presentation: • Fever ... recurrent infections/fevers ... - β-lactam antibiotics ... aplastic anemia Treatment ... #diagnosis #management
Hodgkin's Lymphoma Overview Hodgkin's lymphoma (HL) is an uncommon hematological malignancy arising from mature B cells. It
Hodgkin's lymphoma (HL ... • Dyspnea • Fever ... Hodgkin Lymphoma Treatment ... classification #hematology ... #oncology #management
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