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amiodarone differentiation hematology lung oncology syndrome toxicity
Differentiation Syndrome in APML Epidemiology: • Incidence: common in APL (2-48% depending on the study) • Triggers:
Triggers: ATRA treatment ... endothelial damage • Induce ... Prednisone 5mg/kg ... Imaging: CXR- pulmonary ... #diagnosis #management
Amiodarone Induced Lung Toxicity Summary Who? • 5% of patients • Dose ≥ 400 mg per day How? Possible
Amiodarone Induced ... starting amiodarone treatment ... macrophages Treatment ... #diagnosis #management ... #Toxicology
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