19 results
Disseminated Intravascular Coagulation (DIC) Overview

Increased Clotting and Consumption of Clotting Factors

Findings:
 • Bleeding
 • Recent history
protein C and S Pathophysiology ... Fibrinolysis → End ... organ damage Clinical ... Treat primary cause ... Coagulation #diagnosis #causes
Upper endoscopy revealed a pigmented mass in the duodenal bulb (Panel A) and two additional masses
two additional masses ... duodenum (Panel B) #Clinical ... #GI #Derm #Honc ... Melanoma #Duodenum #EGD ... #Metastatic #NEJM
Chronic Hypertensive Retinopathy: Pathogenesis and clinical findings

Ophthalmic Artery Hypertension
Stage 1: Mild/vasoconstrictive
 • Acute and chronic vasospasm
Pathogenesis and clinical ... hyalinization causes ... BRB breakdown causes ... arterioles causes ... #Retinopathy #pathophysiology
Hemolysis in Hereditary Spherocytosis. Panel A shows the structure of a normal red cell and a
deficiencies that cause ... #Pathophysiology ... #Honc #IM #Spherocytosis ... HereditarySpherocytosis #NEJM
Mallet Finger
Absence of a fracture does NOT exclude Mallet finger, the extension function of the DIP
function of the DIP ... joint needs to be clinically ... Finger deformity caused ... distal to the DIP ... Avulsion fracture • ED
21-Hydroxylase Deficiency (21-OHD): Pathogenesis and Clinical Findings
Autosomal recessive mutation in CYP21A2 coding for the enzyme 21-OHase
Pathogenesis and Clinical ... enzyme 21-OHase causes ... Hirsutism & acne • Infertility ... #21HydroxylaseDeficiency #21OHD #pathophysiology
Heat Illnesses and Heat Stroke - Differential Diagnosis Framework

Heat Cramps:
 • Muscle pain or spasm -
Hypernatremia & end ... Collapse: • Pathophysiology ... cardiomyopathy, ARDS, DIC ... coagulopathy - Possible DIC ... differential #diagnosis #causes
Acute Fatty Liver of Pregnancy (AFLP)
Pathophysiology:
 • Defect in fetal free fatty acid metabolism products →
Pregnancy (AFLP) Pathophysiology ... = nonspecific (nausea ... rapidly develops (DIC ... Maternal Support - Critical ... diagnosis #management #pathophysiology
Immunosuppressive Strategies for the Prevention or Treatment of Acute GVHD. Panel A shows several classic immunosuppressive
are in routine clinical ... been tested in clinical ... #Pathophysiology ... #IM #Honc #Pharm ... Immunosuppression #NEJM
Diabetic Retinopathy: Pathogenesis and clinical findings

Mild Non-proliferative DR
 • Outpouchings of the weakened capillary walls or
Pathogenesis and clinical ... retinal ischemia causes ... neovascularization in the disc ... complications #pathophysiology