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diagnosis ana arthritis autoantibodies clinical differential disease erythematosus laboratory lupus management patterns rheumatic rheumatoid sjogrens syndrome systemic testing workup
Myositis Specific Antibodies (MSAs) Dermatomyositis: MDA5, TIF1y, NXP2, Mi-2, SAE Anti-Synthetase Syndrome: Jo-1, PL7, PL12, EJ, OJ Immune Mediated
Myositis Specific ... Antibodies (MSAs ... #Specific #Antibodies ... #diagnosis #rheumatology ... #table
Antinuclear Antibodies (ANA) ANA or Anti-NucIear Antibody refers to antibodies against antigens in the nucleus → like
Antinuclear Antibodies ... but often not specific ... Sjögren Syndrome, Myositis ... Kumfer @AnnKumfer #Antinuclear ... #patterns #rheumatology
Antinuclear antibodies and Systemic lupus Anti-dsDNA 60-80% Association with disease activity (when with Farr assay) and lupus nephritis. Can
Antinuclear antibodies ... Association with disease ... with auto-immune diseases ... erythematosus #diagnosis #rheumatology ... #table #ANA
Sjogren's Syndrome Overview Epidemiology: • F > M: 9:1 • 5-6th Decades (can be any age) Autoimmune exocrinopathy multisystemic disease
Anti-Ro/SSA ab (specific ... ab • RF • Antinuclear ... antibodies ≥ 1: ... neuropathy, transverse myelitis ... Sjogrens #Syndrome #Rheumatology
Rheumatology Workup - Laboratories Studies in Rheumatic Diseases • Septic arthritis - Gram stain and culture of
Rheumatology Workup ... erythematosus (SLE) - Antinuclear ... double-stranded DNA antibodies ... which are more specific ... level to exclude myositis
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