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diagnosis management ana antinuclear arthritis autoantibodies disease erythematosus laboratory lupus msas myositis polychondritis relapsing rheumatic rheumatoid sjogrens syndrome systemic testing
Myositis Specific Antibodies (MSAs) Dermatomyositis: MDA5, TIF1y, NXP2, Mi-2, SAE Anti-Synthetase Syndrome: Jo-1, PL7, PL12, EJ, OJ Immune Mediated
Myositis Specific ... , TIF1y, NXP2, Mi ... #clinical #diagnosis ... #rheumatology # ... table
Antinuclear antibodies and Systemic lupus Anti-dsDNA 60-80% Association with disease activity (when with Farr assay) and lupus nephritis. Can
Antinuclear antibodies ... Association with disease ... -15% If SLE is clinically ... erythematosus #diagnosis #rheumatology ... #table #ANA
Sjogren's Syndrome Overview Epidemiology: • F > M: 9:1 • 5-6th Decades (can be any age) Autoimmune exocrinopathy multisystemic disease
hypofunction • Antibodies ... Anti-Ro/SSA ab (specific ... IV RTA, TYPE I ... salivary ducts Clinical ... Sjogrens #Syndrome #Rheumatology
Rheumatology Workup - Laboratories Studies in Rheumatic Diseases • Septic arthritis - Gram stain and culture of
Rheumatology Workup ... double-stranded DNA antibodies ... which are more specific ... Tests for All Types ... ANA and RF (if clinical
Relapsing Polychondritis What is it? Recurrent inflammation of the cartilage in the body (Autoimmune disorder) Who? • Most frequently: 40
the most common clinical ... not sensitive or specific ... Anti-Matrilin-1 Ab ○ Antibodies ... to type II collagen ... Polychondritis #rheumatology
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