6 results
Autoimmune Hemolytic Anemia (AIHA) - Differential Diagnosis Table

Warm AIHA (48-70%)
Cold AHA (16-32%)
 • Donath-Landsteiner HA (paroxysmal
Autoimmune Hemolytic Anemia ... Differential Diagnosis Table ... AHA (16-32%) ... Agglutinin Disease ... #hematology
Multiple Myeloma and Monoclonal Gammopathies
C - HyperCalcemia- calcium > 11 mg/dL / >1 mg/dL the ULN
R
Monoclonal Gammopathies ... ULN R - Renal disease ... 40 ml/min A - Anemia ... focal lesions on MRI ... MGUS #diagnosis #hematology
Cold Agglutinin Disease

3 Types of Cold Sensitive Antibodies:
  1. Cold Agglutinins (CAD)
  2. Donath-Landsteiner
- Idiopathic monoclonal ... • Symptoms of anemia ... • hemolytic anemia ... #hemolytic #anemia ... #hematology #diagnosis
Cold Urticaria
Prevalence - 0.05% in the population
Disease onset - Mostly 2nd to 4th decades of life
Causes
Cold Urticaria Prevalence ... clinical associations ... skin contact with cold ... Urticaria #diagnosis #rheumatology ... #comparison #table
Paraproteinemias

Entities That Can Feature A Monoclonal Protein/M Component:
• MM
• WM
• MGUS
• MGCS
• MGRS
• Splenic Marginal Zone
• Heavy Chain disease ... (-) hemolytic anemia ... due to cold IgG ... Sneddon-Wilkinson disease ... Paraproteinemias #Hematology
Behçet's Syndrome
Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy
Epidemiology:
 • Young
Syndrome Systemic disease ... Asia • HLA-B51 association ... matter, spinal cord ... : monoclonal TNF-aIpha ... signs #symptoms #rheumatology