14 results
Inflammatory Myopathies
Dermatomyositis
 • Onset: Subacute
 • Pattern: Proximal
 • CK: Up to 50X ULN
 • Autoantibodies:
Inflammatory Myopathies ... Anti-MDA5, anti-Mi ... #Myopathies #differential ... #rheumatology # ... table
Idiopathic Inflammatory Myopathies (IIM's)

RASH + MUSCLE WEAKNESS → Consider idiopathic inflammatory myopathies (IIM's)

 • Overlap Myositis
Idiopathic Inflammatory ... Myopathies (IIM's ... myopathies (IIM's ... #Myopathies #IIMs ... #diagnosis #rheumatology
Weakness - Differential Diagnosis Framework

Approach To Weakness:
 • Non-neuromuscular disorder (Cardiac, pulmonary etc)
 • CNS ->
- Differential Diagnosis ... • Metabolic myopathies ... EMG) studies • MRI ... certain drug-induced myopathies ... #Differential #Diagnosis
Appearance of Liver Lesions on Various Imaging Modalities
 • Computed Tomography (CT) - Arterial Phase, Portal
Resonance Imaging (MRI ... adenoma (HNF1α, inflammatory ... #Contrast #CT #MRI ... #differential #diagnosis ... #comparison #table
Gout (Gouty Arthritis) - MSK Radiology
Imaging Findings:
 • Eccentric soft-tissue densities surrounding the third proximal interphalangeal
interpreting only MRI ... NOT interpret MRI ... : • Inflammatory ... Has blooming on MRI ... #msk #rheumatology
Myositis Specific Antibodies (MSAs)

Dermatomyositis: MDA5, TIF1y, NXP2, Mi-2, SAE
Anti-Synthetase Syndrome: Jo-1, PL7, PL12, EJ, OJ
Immune Mediated
, TIF1y, NXP2, Mi ... MSAs #clinical #diagnosis ... #rheumatology # ... table
Autoantibodies in Rheumatology
 • Lupus (SLE): ANA (anti-nuclear antibody), dsDNA (double-stranded DNA), Anti-Smith, Anti-Ro (SSA) and
Autoantibodies in Rheumatology ... , Others: SRP, Mi ... Autoantibodies #Rheumatology ... #diagnosis #associations ... #table
Transverse Myelitis Overview

Focal inflammatory disorder of the spinal cord resulting in rapid onset of weakness, sensory
Overview Focal inflammatory ... bouts of HTN Diagnostic ... Transverse Myelitis Diagnosis ... out compressive myelopathies ... Post Vaccine • Inflammatory
SAPHO Syndrome Summary

What?
SAPHO syndrome is a rare chronic inflammatory disorder of bone, joint, and skin characterized
a rare chronic inflammatory ... • A clinical diagnosis ... - MRI: inflammation ... SAPHO #Syndrome #Rheumatology ... #diagnosis #management
Giant cell arteritis (GCA)

Giant cell arteritis (GCA) definition: Most common systemic inflammatory vasculitis in older adults
common systemic inflammatory ... Diagnosis = clinical ... in literature (NEJM ... cases (Cornelia NEJM ... them, but urgent rheumatology