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differential neurology associations autoantibodies comparison management myelitis transverse weakness
Inflammatory Myopathies Dermatomyositis • Onset: Subacute • Pattern: Proximal • CK: Up to 50X ULN • Autoantibodies:
Inflammatory Myopathies ... Anti-MDA5, anti-Mi ... Inclusion Body Myositis ... #rheumatology # ... table
Weakness - Differential Diagnosis Framework Approach To Weakness: • Non-neuromuscular disorder (Cardiac, pulmonary etc) • CNS ->
- Differential Diagnosis ... • Metabolic myopathies ... EMG) studies • MRI ... certain drug-induced myopathies ... #Differential #Diagnosis
Autoantibodies in Rheumatology • Lupus (SLE): ANA (anti-nuclear antibody), dsDNA (double-stranded DNA), Anti-Smith, Anti-Ro (SSA) and
Peptide (CCP) • Myositis ... , Others: SRP, Mi ... Polymerase Ill • ANCA Vasculitis ... #diagnosis #associations ... #table
Transverse Myelitis Overview Focal inflammatory disorder of the spinal cord resulting in rapid onset of weakness, sensory
Overview Focal inflammatory ... Diagnosis: • ... out compressive myelopathies ... Post Vaccine • Inflammatory ... - Sjogren - Vasculitis
Vasculitis - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions • Mononeuritis multiplex • Hematuria, proteinuria,
Diagnosis Framework ... Conjunctivitis, mucositis ... oligoclonal bands • MRI ... syndrome: Ocular inflammatory ... #Rheumatology
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