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diagnosis hematology apml differentiation management monoclonal paraproteinemias
Differentiation Syndrome in APML Epidemiology: • Incidence: common in APL (2-48% depending on the study) • Triggers:
Differentiation Syndrome ... ATRA treatment Pathophysiology ... initiation • Differential ... Differentiation #Syndrome ... #oncology
Paraproteinemias Entities That Can Feature A Monoclonal Protein/M Component: • MM • WM • MGUS • MGCS • MGRS • Splenic Marginal Zone
+Organomegaly+↑RBC ... Autoantibodies: • WAIHA • CAD ... Paraproteinemias #Hematology ... #Monoclonal #Differential ... #Diagnosis #Oncology
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