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diagnosis differential algorithm hypocalcemia management causes secondary signs 21hydroxylasedeficiency 21ohd acromegaly bulimianervosa complications elevated emergencies evaluation genetics hematology hemeonc hormone
Hypercalcemia Workup and Differential Diagnosis Framework 1) Determine whether PTH-dependent 2) Assess for other hormonal causes 3) Assess for
Hypercalcemia Workup ... Determine whether PTH-dependent ... #Workup #Differential ... Diagnosis #algorithm #endocrinology ... #calcium
Parathyroid Hormone (PTH) Effect in Calcium and Phosphorus Calcium - Net Effect Hypercalcemia: ↑ intestinal
Parathyroid Hormone (PTH ... - Net Effect Hypercalcemia ... Parathyroid #Hormone #PTH ... #Phosphorus #pathophysiology ... #endocrinology
Hypocalcemia - Diagnosis and Management PTH Independent (↑ PTH) • LOW VIT D -
Hypocalcemia - Diagnosis ... - Calcium Sequestration ... - DiGeorge Syndrome ... Signaling #Hypocalcemia ... Diagnosis #Management #endocrinology
Hyperparathyroidism - Primary vs Secondary vs Tertiary Lab Comparison: • Primary Hyperparathyroidism: ↑→PTH, ↑Calcium, ↑Vitamin D,
, ↑Calcium, ↑Vitamin ... Phosphate Physical Symptoms ... pain Psychiatric Symptoms ... Hyperparathyroidism #diagnosis #endocrinology ... Secondary #Tertiary #pathophysiology
Hypocalcemia Workup - Differential Diagnosis Algorithm • Low Magnesium, High Magnesium - Functional Hypoparathyroidism • High
Hypocalcemia Workup ... Phosphate, Low PTH ... Phosphate, High PTH ... metastases, Hungry bone syndrome ... #Workup #Differential
Hypercalcemia Evaluation 1) Clinical clues - Is the patient symptomatic? - Family history? - Have you done
Hypercalcemia Evaluation ... 2) PTH - Frankly ... #diagnosis #endocrinology ... #calcium #elevated ... #evaluation #workup
Hypocalcemia - Differential Diagnosis Algorithm - Low and High Phosphate LOW PHOSPHATE - Low/NormaI PTH
Hypocalcemia - Differential ... Phenytoin, Nephrotic Syndrome ... Activating Mutation in Calcium ... Poisoning #Hypocalcemia ... Algorithm #Phosphate #endocrinology
Leukostasis vs Tumor Lysis Syndrome Leukostasis: • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
Leukostasis: • Pathophysiology ... Dehydration • Symptoms ... changes, stroke symptoms ... : • Pathophysiology ... hydration - Hyperkalemia
21-Hydroxylase Deficiency (21-OHD): Pathogenesis and Clinical Findings Autosomal recessive mutation in CYP21A2 coding for the enzyme 21-OHase
Signs/Symptoms/Complications ... : • Hyperkalemia ... Hirsutism & acne • Infertility ... #21HydroxylaseDeficiency #21OHD #pathophysiology ... #genetics #endocrinology
Sarcoidosis - Diagnosis and Management Summary Epidemiology 1) High incidence in Scandinavian countries (11-24 cases per 100,000 individuals
survival is 93-95% Pathophysiology ... fibrosis. 4) Calcium ... hyperphosphatemia, hypercalcemia ... mediators such as hypercalcaemia ... patients) and/or hypercalcuria
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