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diagnosis differential management signs algorithm hypocalcemia primary 21hydroxylasedeficiency 21ohd adrenal alkaline alp arthropathies arthropathy bulimianervosa causes complications disorders genetics hematology
Hyperparathyroidism - Primary vs Secondary vs Tertiary Lab Comparison: • Primary Hyperparathyroidism: ↑→PTH, ↑Calcium, ↑Vitamin D,
↓Phosphate • Secondary ... Phosphate Physical Symptoms ... pain Psychiatric Symptoms ... Hyperparathyroidism #diagnosis #endocrinology ... #Tertiary #pathophysiology
Hypocalcemia - Differential Diagnosis Algorithm - Low and High Phosphate LOW PHOSPHATE - Low/NormaI PTH
Hypocalcemia - Differential ... Phenytoin, Nephrotic Syndrome ... High PTH • Secondary ... Poisoning #Hypocalcemia ... Algorithm #Phosphate #endocrinology
Patellofemoral Syndrome - Pathogenesis and clinical findings • Anterior Knee Pain with possible symptoms of 'catching'
Patellofemoral Syndrome ... with possible symptoms ... (crepitus) • Secondary ... #pathophysiology ... #msk
Leukostasis vs Tumor Lysis Syndrome Leukostasis: • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
Leukostasis: • Pathophysiology ... Dehydration • Symptoms ... changes, stroke symptoms ... : • Pathophysiology ... hydration - Hyperkalemia
21-Hydroxylase Deficiency (21-OHD): Pathogenesis and Clinical Findings Autosomal recessive mutation in CYP21A2 coding for the enzyme 21-OHase
Signs/Symptoms/Complications ... : • Hyperkalemia ... Hirsutism & acne • Infertility ... #21HydroxylaseDeficiency #21OHD #pathophysiology ... #genetics #endocrinology
Joint Disorders - Differential Diagnosis Algorithm Monoarthritis • Septic • Crystalline - Gout
“Pseudogout” - Calcium ... arthritis - (Reiter’s syndrome ... inflammation is secondary ... should have other symptoms ... Joint #Disorders #msk
Sarcoidosis - Diagnosis and Management Summary Epidemiology 1) High incidence in Scandinavian countries (11-24 cases per 100,000 individuals
survival is 93-95% Pathophysiology ... fibrosis. 4) Calcium ... hyperphosphatemia, hypercalcemia ... patients) and/or hypercalcuria ... anterior/posterior MSK
Causes of Hypocalcemia by Clinical Cause Acute illness: pancreatitis, tumor lysis, severe illness - Secondary hyperparathyroidism from
severe illness - Secondary ... low circulating calcium ... Malabsorption syndrome ... Renal disease - Secondary ... Differential #Diagnosis #Endocrinology
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 Adrenal Insufficiency - Diagnosis and Management Summary Primary Adrenal Insufficiency: Most Common Cause in the US: Autoimmune Adrenalitis Other
ketoconazole, etomidate) Symptoms ... Hyperkalemia is ... Causes of Secondary ... hypophysitis, Sheehan's syndrome ... Diagnosis #Management #Endocrinology
Low Alkaline Phosphatase - Hypophosphatasia Is Low Alkaline Phosphatase Of Clinical Importance? ALP enzyme- Discovered in 1923 Low
pain • loss of secondary ... collection with EDTA Pathophysiology ... ALP -> PPi and Calcium ... mineralization Symptoms ... Hyperlipidemia - Hypercalcemia
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