11 results
Feedback Loop: Growth Hormone (GH)
Growth Hormone:
 • Liver -> GHR activates JAK-STAT pathway -> Incr IGF1
Feedback Loop: Growth Hormone ... (GH) Growth Hormone ... activates lipolysis Signs ... #FeedbackLoop #endocrinology ... #pathophysiology
Acromegaly 
Caused by over-secretion of growth hormone (GH) from the pituitary gland. 
The condition is rare
over-secretion of growth hormone ... (GH) from the pituitary ... #Acromegaly #Signs ... #Symptoms #Diagnosis ... #Endocrinology
Growth Hormone Excess - Pathogenesis and clinical findings
 • Acromegaly and gigantism share the same pathophysiology
Growth Hormone Excess ... Carpal Tunnel Syndrome ... Overproduction #diagnosis ... #signs #symptoms ... #endocrinology
Pituitary Mass Effects - Pathogenesis and Clinical Findings
 • Pituitary turnors are almost always a benign
common), growth hormone ... ) the anterior hormones ... most essential hormones ... the order the hormones ... Loss of pituitary hormones
Weight Gain / Obesity  - Differential Diagnosis Algorithm
Decreased Expenditure:
 • Sedentary Lifestyle
 • Smoking Cessation
- Differential Diagnosis ... • Cushing's Syndrome ... Hypogonadism • GH ... Iatrogenic: • Drugs/Hormones ... #Algorithm #endocrinology
Causes of Hypocalcemia by Clinical Cause

Acute illness: pancreatitis, tumor lysis, severe illness - Secondary hyperparathyroidism from
or parathyroid hormone ... Malabsorption syndrome ... absent parathyroid hormone ... #Differential #Diagnosis ... #Endocrinology
Pseudogout: pathogenesis and clinical findings
 - Idiopathic (vast majority of cases) -> Mechanism unknown
 - Familial
of parathyroid hormone ... > Clearance of calcium ... CPPD #Disease #Signs ... #Symptoms #Pathophysiology ... #Diagnosis
Bulimia Nervosa: Complications
GASTROINTESTINAL
 • Dehydration & inability to digest food -> Constipation
 • Recurrent vomiting exposes
• Boerhaave syndrome ... of nutrients, hormonal ... Calcium, VitD) and ... lowered hormone ... #diagnosis #signs
Causes of Secondary Hypertension - Workup and Differential Diagnosis
Approach (when evaluation should be done):
1. Severe or
and Differential Diagnosis ... hypertension and signs ... renal bruit or signs ... of hormonal excess ... Vasculitis • Endocrinologic
Sarcoidosis - Diagnosis and Management Summary
Epidemiology
1) High incidence in Scandinavian countries (11-24 cases per 100,000 individuals
Sarcoidosis - Diagnosis ... -55; f 50-60y (hormonal ... survival is 93-95% Pathophysiology ... fibrosis. 4) Calcium ... #Management #Signs