11 results
Feedback Loop: Growth Hormone (GH)
Growth Hormone:
 • Liver -> GHR activates JAK-STAT pathway -> Incr IGF1
(GH) Growth Hormone ... activates lipolysis Signs ... #FeedbackLoop #endocrinology ... #pathophysiology ... #pituitary
Acromegaly 
Caused by over-secretion of growth hormone (GH) from the pituitary gland. 
The condition is rare
over-secretion of growth hormone ... (GH) from the pituitary ... #Acromegaly #Signs ... Symptoms #Diagnosis #Endocrinology
Pituitary Mass Effects - Pathogenesis and Clinical Findings
 • Pituitary turnors are almost always a benign
common), growth hormone ... following order; GH ... Signs / Symptoms ... #SideEffects #endocrinology ... mnemonic #GLFTAP #pathophysiology
Growth Hormone Excess - Pathogenesis and clinical findings
 • Acromegaly and gigantism share the same pathophysiology
Growth Hormone Excess ... Carpal Tunnel Syndrome ... Overproduction #diagnosis #signs ... #symptoms #endocrinology ... #pathophysiology
Acromegaly - Diagnosis and Management Summary - GrepMed Handbook 

Clinical Presentation: 
 • Classic Acromegaly: frontal
malignancy Pathophysiology ... Beckwith Wiedemann syndrome ... • Pituitary ... Diagnosis #Management #Endocrinology ... #Treatment #Pathophysiology
Cushing Syndrome Testing Algorithm
INDICATIONS FOR TESTING:
 • Suspected Cushing syndrome (central obesity, muscle weakness, refractory hypertension)
Testing:
Testing Algorithm ... Adrenocorticotropic Hormone ... adrenal glands, pituitary ... #diagnosis #algorithm ... #endocrinology
Weight Gain / Obesity  - Differential Diagnosis Algorithm
Decreased Expenditure:
 • Sedentary Lifestyle
 • Smoking Cessation
Differential Diagnosis Algorithm ... • Cushing's Syndrome ... Hypogonadism • GH ... Iatrogenic: • Drugs/Hormones ... #endocrinology
Algorithmic Approach to Hypothyroidism - Differential Diagnosis and Management Framework

Central Hypothyroidism (Secondary or tertiary) ↓TSH, ↓FT4
Algorithmic Approach ... ↓FT4 • Post-GH ... drug-induced • Pituitary ... Euthyroid sick syndrome ... #endocrinology
Acromegaly Testing Algorithm
INDICATIONS FOR TESTING:
 • Adults – enlarged facial or acral features, abnormal musculoskeletal growth
Acromegaly Testing Algorithm ... load • Growth Hormone ... (GH) test (2 hours ... MRI to evaluate pituitary ... #diagnosis #endocrinology
Menstrual Cycle Physiology: Ovarian Cycle – Follicular Phase Explained
Early Follicular Phase (Days 0-5)
 • Granulosa cells
secrete activin, a hormone ... production by pituitary ... Polycystic Ovarian Syndrome ... #OvarianCycle #pathophysiology ... FollicularPhase #endocrinology