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acromegaly symptoms differential growthhormone management adrenal bulimianervosa causes complications cushing excess feedbackloop glftap hyperfunction hypothyroid hypothyroidism macroadenoma masseffects mnemonic obesity
Acromegaly Caused by over-secretion of growth hormone (GH) from the pituitary gland. The condition is rare
over-secretion of growth hormone ... (GH) from the pituitary ... #Acromegaly #Signs ... #Symptoms #Diagnosis ... #Endocrinology
Feedback Loop: Growth Hormone (GH) Growth Hormone: • Liver -> GHR activates JAK-STAT pathway -> Incr IGF1
(GH) Growth Hormone ... activates lipolysis Signs ... #FeedbackLoop #endocrinology ... #pathophysiology ... #pituitary
Pituitary Mass Effects - Pathogenesis and Clinical Findings • Pituitary turnors are almost always a benign
common), growth hormone ... following order; GH ... Signs / Symptoms ... #SideEffects #endocrinology ... mnemonic #GLFTAP #pathophysiology
Growth Hormone Excess - Pathogenesis and clinical findings • Acromegaly and gigantism share the same pathophysiology
Growth Hormone Excess ... Carpal Tunnel Syndrome ... Overproduction #diagnosis ... #signs #symptoms ... #endocrinology
Acromegaly - Diagnosis and Management Summary - GrepMed Handbook Clinical Presentation: • Classic Acromegaly: frontal
Acromegaly - Diagnosis ... malignancy Pathophysiology ... Beckwith Wiedemann syndrome ... #Management #Endocrinology ... #Treatment #Pathophysiology
Weight Gain / Obesity - Differential Diagnosis Algorithm Decreased Expenditure: • Sedentary Lifestyle • Smoking Cessation
- Differential Diagnosis ... Algorithm Decreased ... Hypogonadism • GH ... Iatrogenic: • Drugs/Hormones ... #Algorithm #endocrinology
Cushing Syndrome Testing Algorithm INDICATIONS FOR TESTING: • Suspected Cushing syndrome (central obesity, muscle weakness, refractory hypertension) Testing:
Testing Algorithm ... Adrenocorticotropic Hormone ... adrenal glands, pituitary ... #diagnosis #algorithm ... #endocrinology
Algorithmic Approach to Hypothyroidism - Differential Diagnosis and Management Framework Central Hypothyroidism (Secondary or tertiary) ↓TSH, ↓FT4
Algorithmic Approach ... ↓FT4 • Post-GH ... drug-induced • Pituitary ... Euthyroid sick syndrome ... #algorithm #endocrinology
Acromegaly Testing Algorithm INDICATIONS FOR TESTING: • Adults – enlarged facial or acral features, abnormal musculoskeletal growth
Acromegaly Testing Algorithm ... load • Growth Hormone ... (GH) test (2 hours ... MRI to evaluate pituitary ... #diagnosis #endocrinology
Bulimia Nervosa: Complications GASTROINTESTINAL • Dehydration & inability to digest food -> Constipation • Recurrent vomiting exposes
• Boerhaave syndrome ... of nutrients, hormonal ... > Amenorrhea & Infertility ... Complications #pathophysiology ... #diagnosis #signs
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