8 results
Acromegaly 
Caused by over-secretion of growth hormone (GH) from the pituitary gland. 
The condition is rare
Acromegaly Caused ... over-secretion of growth hormone ... (GH) from the pituitary ... #Acromegaly #Signs ... Symptoms #Diagnosis #Endocrinology
Pituitary Mass Effects - Pathogenesis and Clinical Findings
 • Pituitary turnors are almost always a benign
following order; GH ... Signs / Symptoms ... • Nausea and ... #SideEffects #endocrinology ... mnemonic #GLFTAP #pathophysiology
Feedback Loop: Growth Hormone (GH)
Growth Hormone:
 • Liver -> GHR activates JAK-STAT pathway -> Incr IGF1
(GH) Growth Hormone ... activates lipolysis Signs ... #FeedbackLoop #endocrinology ... #pathophysiology ... #pituitary
Growth Hormone Excess - Pathogenesis and clinical findings
 • Acromegaly and gigantism share the same pathophysiology
Growth Hormone Excess ... • Other rare causes ... Carpal Tunnel Syndrome ... Overproduction #diagnosis #signs ... #symptoms #endocrinology
Acromegaly - Diagnosis and Management Summary - GrepMed Handbook 

Clinical Presentation: 
 • Classic Acromegaly: frontal
Usually presents ~5th ... malignancy Pathophysiology ... Beckwith Wiedemann syndrome ... or refractory cases ... Diagnosis #Management #Endocrinology
Causes of Secondary Hypertension - Workup and Differential Diagnosis
Approach (when evaluation should be done):
1. Severe or
hypertension and signs ... renal bruit or signs ... of hormonal excess ... Vasculitis • Endocrinologic ... apnea: CPAP, most pts
Sarcoidosis - Diagnosis and Management Summary
Epidemiology
1) High incidence in Scandinavian countries (11-24 cases per 100,000 individuals
-55; f 50-60y (hormonal ... survival is 93-95% Pathophysiology ... fibrosis. 4) Calcium ... symptoms are not caused ... Diagnosis #Management #Signs
Bulimia Nervosa: Complications
GASTROINTESTINAL
 • Dehydration & inability to digest food -> Constipation
 • Recurrent vomiting exposes
• Boerhaave syndrome ... > Amenorrhea & Infertility ... Calcium, VitD) and ... levels cause bones ... #diagnosis #signs