48 results
Prader-Willi Syndrome: Pathogenesis and clinical findings
 • Maternal uniparental disomy: inheriting 2 copies of maternal chromosome
Pathogenesis and clinical ... Signs/Symptoms ... delayed puberty -> Infertility ... pathophysiology #peds ... #pediatrics
Kawasaki Disease (Mucocutaneous Lymph Node Syndrome) 
An rare systemic acute febrile vasculitic syndrome. Aetiology unknown. 
Affects
Kawasaki Disease ... Early diagnosis ... #Kawasaki #Disease ... #Features #Signs ... #Peds #Pediatrics
Epiglottitis - Swollen inflamed epiglottis 
Clinical (Rapid onset) 
 • Fever 
 • Sore throat
inflamed epiglottis Clinical ... #Epiglottitis #Signs ... #Causes #Diagnosis ... #Differential #Peds ... #Pediatrics
Brudzinski’s Sign in Meningitis (first described in 19th century by Dr. Josef Brudzinski)

Brudzinski's sign is characterized
Passive neck flexion causes ... despite severe disease ... #Meningitis #Clinical ... #PhysicalExam #Pediatrics ... #Peds
Major neurocognitive disorders (MNCD): Diagnosis and workup 

1) Clinical diagnosis Cognitive impairment + loss of autonomy
2)
1) Clinical diagnosis ... Alzheimer - 1st cause ... Aphaso-apraxo-agnosia syndrome ... (parkinsonian signs ... #Diagnosis #Geriatrics
Alzheimer’s Disease: Pathogenesis and Clinical Findings
Risk factor for Late Onset Alzheimer's (99% of cases):
 - Increasing
Alzheimer’s Disease ... Pathogenesis and Clinical ... mutations - Down syndrome ... chromosome 21) Signs ... #diagnosis #signs
Syncope is a sudden, transient loss of consciousness, which is thought to be secondary to cerebral
structural heart disease ... carotid sinus syndrome ... orthostatic vital sign ... should be guided by clinical ... The treatment strategy
Portal Hypertension - Differential Diagnosis
Portal Pressure = the pressure difference between the pressure in the portal
- Differential Diagnosis ... >10 mmHg - clinically ... significant portal HTN Signs ... and hepatorenal syndrome ... obstruction) • Lack of signs
Causes of Urinary Incontinence - Differential Diagnosis Algorithm
 - Transient - Easily reversible cause (DIAPPERS)
- Differential Diagnosis ... Contraction - Signs ... or spinal cord disease ... , cauda equina syndrome ... #Differential #Diagnosis
Peri-operative Hyperthermia - Guidelines for Crises in Anaesthesia
If prolonged or ≥ 39 C this is a
39 C this is a clinical ... Treatment depends ... hyperthermia crisis (late sign ... Anesthesia #Checklist #Diagnosis ... #Management #Workup