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diagnosis differential rheumatology algorithm dermatology syndrome acidosis cryoglobulinemia cryoglobulins diseases elevation erythematosus glomerulonephritis hypertension ild interstitial lactate lactic lung management
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
progressing GN • New pulmonary ... tract, and often causes ... inflammation Others: • Lupus ... such as systemic lupus ... #classification
Interstitial Lung Diseases (ILD) Exposure-Related ILD (a.k.a. extrinsic allergic alveolitis): • Hypersensitivity pneumonitis, Farmer's lung, Bird
ILD caused by inhalation ... pneumonitis • Medication-induced ... Polymyositis-dermatomyositis, Lupus ... Sarcoidosis • Vasculitis ... #causes
Rapidly Progressive Glomerulonephritis (RPGN) RPGN has three primary pathophysiologic causes differentiated by immunofluorescence Immune Complex Mediated (granular staining):
pathophysiologic causes ... Post-strep GN, Lupus ... With associated pulmonary ... Glomerulonephritis #Vasculitis ... diagnosis #algorithm #rheumatology
Clinical Classification of Pulmonary Hypertension 1. Pulmonary arterial hypertension from pulmonary vasculopathy Idiopathic pulmonary arterial hypertension Heritable gene mutations
Clinical Classification ... multifactorial mechanisms Hematologic ... neurofibromatosis, vasculitis ... Hypertension #PHTN #Classification ... #Differential #Causes
Causes of Petechial Rash - Differential Diagnosis Algorithm Pinpoint areas (less than 2 mm) of hemorrhage, which
Causes of Petechial ... Infection - Vasculitis ... Immunosuppressed • New medication ... - Autoimmune Vasculitis ... (lupus, RA, Sjogren's
Cryoglobulinemia Summary Cryoglobulins: • Cryoglobulins are Igs in the serum that precipitate in vitro at temperatures below
• They can cause ... Cryoglobulins Cause ... (e.g. systemic lupus ... diagnosis #types #classification ... #rheumatology #
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
Skin Disease Classification ... ANCA-associated vasculitis ... Malignancy (e.g. hematologic ... • Mesenteric vasculitis ... activation and/or medications
Causes of Lactate Elevation, Lactic Acidosis - Differential Diagnosis The most common causes of hyperlactatemia are usually:
perfusion - shock->treatments ... before beginning treatment ... output - Acute pulmonary ... - HIV/HAART medications ... #typea #typeb #classification
Sweet Syndrome Acute febrile neutrophilic dermatosis (Sweets Syndrome) is a skin condition characterized by fever and inflamed
Causes: - Idiopathic ... , breast CA - Hematologic ... Leukocytoclastic vasculitis ... ’s syndrome - Lupus ... Treatment: - Systemic
Sjogren's Syndrome Overview Epidemiology: • F > M: 9:1 • 5-6th Decades (can be any age) Autoimmune exocrinopathy multisystemic disease
Hypocomplementemia • Can cause ... , INC risk PE, Pulmonary ... ) • Cutaneous vasculitis ... : 2% Systemic Vasculitis ... Adenocarcinoma Treatment
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