8 results
Hydroxychloroquine Serum Measurement in SLE
 • Terminal elimination half-life = 40 days ([HCQI reflects long-term intake)
Hydroxychloroquine ... half-life = 40 days ([HCQI ... 200ng/mL Best indications ... #SLE #rheumatology ... pharmacology #levels #lupus
Hydroxychloroquine - Risks and Benefits in Lupus
Benefits:
↓ Disease activity, ↓ Flare, ↓ Damage, ↓ Corticosteroid dose,
Hydroxychloroquine ... and Benefits in Lupus ... recommended with other medications ... #hcq #Risks #Benefits ... #Lupus #pharmacology
Hydroxychloroquine is an antimalarial & DMARD (disease modifying antirheumatic drug). It is currently being discussed as
prophylaxis and treatment ... tinnitus) and may cause ... It also can cause ... who require this medication ... #HCQ #Pharmacology
Drug Induced Lupus vs SLE
Drug Induced Lupus (DIL):
 • Epidemiology: -10% of all lupus cases, drug-dependent,
constitutional symptoms • Treatment ... Discontinuation of causal ... drug +++, Hydroxychloroquine ... life-threatening • Treatment ... comparison #table #rheumatology
Drug Induced Liver Injury (DILI) - Stepwise Diagnosis Algorithm
DILI suspicion
Features toxic aetiology: Skin involvement, Kidney injury,
duration), Several medications ... non-essential drug/HDS treatments ... for alternative causes ... infections (HAV, HBV, HCV ... Diagnosis #Algorithm #hepatology
Drug Induced Lupus (DIL)
 • Epidemiology: -10% of all lupus cases, drug-dependent, 4:1 to 1:1 F:M
constitutional symptoms • Treatment ... Discontinuation of causal ... drug +++, Hydroxychloroquine ... #DIL #rheumatology ... #diagnosis #treatment
Vasculitis and Vasculitides - Differential Diagnosis Framework

When to Consider Vasculitis:
 • Purpura, ischemic skin lesions
 •
progressing GN • New pulmonary ... tract, and often causes ... inflammation Others: • Lupus ... such as systemic lupus ... • HIV • HBV HCV
Aplastic Anemia - Overview

Who?
• M = F
• 3 peaks:	1) Childhood	2) 15-25 years	3) >60 years

What?
• Aplastic anemia
and petechiae Causes ... - Antithyroid medications ... - CMV - HCV ... aplastic anemia Treatment ... Anemia #oncology #hematology