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rheumatology diagnosis druginduced management pharmacology sle adverseeffects algorithm benefits comparison dili hepatology injury levels liver measurement risks serum sideeffects table
Hydroxychloroquine Serum Measurement in SLE • Terminal elimination half-life = 40 days ([HCQI reflects long-term intake)
Hydroxychloroquine ... half-life = 40 days ([HCQI ... 200ng/mL Best indications ... #SLE #rheumatology ... pharmacology #levels #lupus
Drug Induced Lupus vs SLE Drug Induced Lupus (DIL): • Epidemiology: -10% of all lupus cases, drug-dependent,
constitutional symptoms • Treatment ... Discontinuation of causal ... drug +++, Hydroxychloroquine ... life-threatening • Treatment ... comparison #table #rheumatology
Hydroxychloroquine - Risks and Benefits in Lupus Benefits: ↓ Disease activity, ↓ Flare, ↓ Damage, ↓ Corticosteroid dose,
Hydroxychloroquine ... and Benefits in Lupus ... recommended with other medications ... #hcq #Risks #Benefits ... #Lupus #pharmacology
Drug Induced Liver Injury (DILI) - Stepwise Diagnosis Algorithm DILI suspicion Features toxic aetiology: Skin involvement, Kidney injury,
duration), Several medications ... non-essential drug/HDS treatments ... for alternative causes ... infections (HAV, HBV, HCV ... Diagnosis #Algorithm #hepatology
Drug Induced Lupus (DIL) • Epidemiology: -10% of all lupus cases, drug-dependent, 4:1 to 1:1 F:M
constitutional symptoms • Treatment ... Discontinuation of causal ... drug +++, Hydroxychloroquine ... #DIL #rheumatology ... #diagnosis #treatment
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