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rheumatology diagnosis management druginduced pharmacology adverseeffects benefits classification comparison differential dil levels measurement risks serum sideeffects table vasculitides vasculitis
Hydroxychloroquine Serum Measurement in SLE • Terminal elimination half-life = 40 days ([HCQI reflects long-term intake)
Hydroxychloroquine ... Measurement in SLE ... 200ng/mL Best indications ... #SLE #rheumatology ... pharmacology #levels #lupus
Drug Induced Lupus vs SLE Drug Induced Lupus (DIL): • Epidemiology: -10% of all lupus cases, drug-dependent,
constitutional symptoms • Treatment ... Discontinuation of causal ... drug +++, Hydroxychloroquine ... life-threatening • Treatment ... #table #rheumatology
Hydroxychloroquine - Risks and Benefits in Lupus Benefits: ↓ Disease activity, ↓ Flare, ↓ Damage, ↓ Corticosteroid dose,
Hydroxychloroquine ... and Benefits in Lupus ... recommended with other medications ... #hcq #Risks #Benefits ... #Lupus #pharmacology
Drug Induced Lupus (DIL) • Epidemiology: -10% of all lupus cases, drug-dependent, 4:1 to 1:1 F:M
is rare in DIL, SCLE-DIL ... Discontinuation of causal ... drug +++, Hydroxychloroquine ... #DIL #rheumatology ... #diagnosis #treatment
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
tract, and often causes ... inflammation Others: • Lupus ... such as systemic lupus ... vasculitis, and SLE ... • HIV • HBV HCV
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