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diagnosis differential management syndrome arthritis erythematosus joint sle systemic vasculitis workup activation algorithm ana antibodies antinuclear approach cancer capillary clarksons
Antinuclear Antibodies (ANA) ANA or Anti-NucIear Antibody refers to antibodies against antigens in the nucleus → like
assay (IFA) is the main ... , Drug-induced Lupus ... , Drug-Induced Lupus ... , Interstitial Pulmonary ... ANA #patterns #rheumatology
Holistic Management of Systemic Lupus • Lifestyle interventions: Smoking cessation, Photoprotection, Therapeutic adherence, Anxiety/depression/fatigue, Fibromyagia/pain management,
Management of Systemic Lupus ... fatigue, Fibromyagia/pain ... • Pregnancy & fertility ... Erythematosus #management #treatment ... #rheumatology
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
Non-autoimmune rheumatologic ... Malignancy (e.g. hematologic ... Arthritis: • Joint pain ... activation and/or medications ... Erythematosus #Diagnosis #Rheumatology
Macrophage Activation Syndrome (MAS) Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH) What? A subset of
• Systemic lupus ... • Fever is the main ... Treatment: • Corticosteroids ... Diagnosis #Management #Hematology ... #Rheumatology
Extra-articular and Other Conditions Associated with Joint Pain Eyes • Iritis or uveitis - Spondyloarthropathies, Sarcoidosis,
Associated with Joint Pain ... Nodules • RA • Gout ... Tophi - Gout ... Pulmonary ... differential #diagnosis #rheumatology
Approach to Joint Pain - Diagnostic Framework 1) Chronicity 2) Inflammatory vs Non-Inflammatory 3) Number of Joints Involved 1) Chronicity:
Approach to Joint Pain ... ), RA, crystal disease ... spondyloarthropathies, lupus ... #Joint #Pain #MSK ... #rheumatology #
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
inflammation Others: • Lupus ... such as systemic lupus ... Vessels: Supply gut ... , testes -> pain ... differential #diagnosis #rheumatology
Gout - Diagnosis and Management Summary 3 Conditions for Gout to Manifest: 1. Hyperuricemia 2. Monosodium urate deposition in
Metabolic syndrome • Medications ... swelling, significant pain ... cortical bone Treatment ... treatment; consider ... #rheumatology
CPPD vs Gout == CPPD == Think About CPPD When: • Self-limited synovitis after surgery/trauma (> 65
• Underlying disease ... onset of swelling, pain ... Metabolic syndrome • Medications ... swelling, significant pain ... #Comparison #rheumatology
SAPHO Syndrome Summary What? SAPHO syndrome is a rare chronic inflammatory disorder of bone, joint, and skin characterized
lesions + Rheumatic pain ... diagnosis • Rule out ... and lower jaw Treatment ... osteoarticular and skin disease ... SAPHO #Syndrome #Rheumatology
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