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diagnosis management antibiotic aspergillus betadglucan causes comparison failure galactomannan granuloma immune infectiousdiseases inflammatory iris lung majocchis microscopy mycoses pulmonary reconstitution
Fungal Biomarkers: Beta-D-Glucan and Aspergillus Galactomannan Beta-D-Glucan: • Polysaccharide cell wall component of many fungi • Pathogens:
Fungal Biomarkers ... infection (IFI) ... cut-offs defined in clinical ... surfaces - Infections ... GM does not differentiate
Causes of Antibiotic Failure - Differential Diagnosis Framework Diagnosis: • Non-Infectious: Malignant, Autoimmune, Drug-related (NMS, serotonin syndrome,
Antibiotic Failure - Differential ... , VTE • Wrong Bug ... bacteria: Viral, Fungal ... Source control (abscess ... • Secondary to Treatment
Lung Abscess - Diagnosis and Management Summary Lung Abscess Etiology: • Necrosis of lung parenchyma by a
polymicrobial infection ... Lung Abscess - Clinical ... Prevotella • Fungal ... Differential Diagnosis ... #pulmonary #differential
Immune Reconstitution Inflammatory Syndrome - Overview of IRIS What Is IRIS? • A state of hyperinflammatory response that
noncompliance • Clinical ... initiation Clinical ... osteomyelitis, cutaneous abscesses ... Calmette-Guérin (BCG ... Leishmaniasis Differential
Majocchi’s Granuloma due to Trichophyton rubrum This is GMS stain and culture of a skin biopsy
Treatment: Itraconazole ... plaques, pustules, abscess ... Fungal infection ... recommended Mayo Clinic ... #photo #microscopy
Mycoses HISTOPLASMOSIS • Inhalation of conidia → Yeast → travel to lymph nodes → spread in body • Bird
body • Bird and bat ... has five major clinical ... Diagnosis: • Direct fungal ... stain of clinical ... Sinusitis • Brain abscess
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