11 results
Purple Urine Bag Syndrome
Chronic, indwelling catheter + bacteriuria (Providencia, Klebsiella, E.coli*) + alkaline urine
Tryptophan → Indoxyl
Purple Urine Bag ... Purple #Urine #Bag ... Syndrome #PUBS #pathophysiology ... #clinical #photo ... #differential #
Fungal Biomarkers: Beta-D-Glucan and Aspergillus Galactomannan
Beta-D-Glucan:
 • Polysaccharide cell wall component of many fungi
 • Pathogens:
Fungal Biomarkers ... component of many fungi ... cut-offs defined in clinical ... GM does not differentiate ... admin of mold-active
Causes of Antibiotic Failure - Differential Diagnosis Framework
Diagnosis:
 • Non-Infectious: Malignant, Autoimmune, Drug-related (NMS, serotonin syndrome,
Antibiotic Failure - Differential ... , VTE • Wrong Bug ... bacteria: Viral, Fungal ... ocular), Tissue activity ... • Secondary to Treatment
Humoral Immunity - Pathogenesis and Clinical Findings
Antigens (Ag) are produced from pathogens (bacteria, viruses, fungi, parasites)
Pathogenesis and Clinical ... bacteria, viruses, fungi ... helper T cells and activate ... proliferate and differentiate ... Humoral #Immunity #pathophysiology
1,3-Beta-D-Glucan and Galactomannan Testing Sensitivity Specificity and False Positives
1,3-Beta-D-Glucan
 • Cell wall component of many fungi
component of many fungi ... cut-offs defined in clinical ... >90% (In most clinical ... does not differentiate ... concurrent admin mold-active
Tuberculosis Overview

10 million new M. tuberculosis infections/year
Facultative intracellular rod-shaped bacteria
Multidrug-resistant tuberculosis (MDR-TB) accounts for 4.6% of
tuberculosis (LTBI) Pathophysiology ... infection (NTM) • Fungal ... characteristic features Clinical ... Tuberculosis Treatment ... Initiating Treatment
Tuberculosis Overview

10 million new M. tuberculosis infections/year
Facultative intracellular rod-shaped bacteria
Multidrug-resistant tuberculosis (MDR-TB) accounts for 4.6% of
tuberculosis (LTBI) Pathophysiology ... infection (NTM) • Fungal ... characteristic features Clinical ... Tuberculosis Treatment ... Initiating Treatment
Lung Abscess - Diagnosis and Management Summary

Lung Abscess Etiology:
 • Necrosis of lung parenchyma by a
Lung Abscess Pathophysiology ... Lung Abscess - Clinical ... Prevotella • Fungal ... Lung Abscess Differential ... Abscess #pulmonary #differential
Amyotrophic Lateral Sclerosis (ALS) Summary
ALS: combination of the clinical examination finding of amyotrophy with the pathologic
lateral sclerosis Pathophysiology ... Excessive glutamate activity ... conditions listed in differential ... diagnosis column Treatment ... by decreasing activity
Immune Reconstitution Inflammatory Syndrome - Overview of IRIS

What Is IRIS?
	• A state of hyperinflammatory response that
noncompliance • Clinical ... initiation Clinical ... Calmette-Guérin (BCG ... Leishmaniasis Differential ... • Persistently active