9 results
Vasopressors and Inotropes - Pharmacology Summary
Vasopressors
Phenylephrine (alpha-1)
 • Increases BP, SVR
 • Risk of reflex bradycardia
- Pharmacology ... first agent in shock ... line in septic shock ... cAMP/cGMP • Causes ... #Pharmacology #
Shock - Pathophysiology 
Inadequate tissue perfusion to meet O2, nutrient requirements
1. Distributive Shock
2. Hypovolemic Shock
3. Cardiogenic
Shock - Pathophysiology ... Hypovolemic Shock ... #Shock #Pathophysiology ... differential #diagnosis #algorithm ... #causes
Common Vasopressors and Inotropes
Norepinephrine (NE)
 - Indication: Distributive shock (1st line for septic shock), Cardiogenic shock
Vasopressors and Inotropes ... : Distributive shock ... Bradyarrhythmias, Some cases ... #Vasopressors #Inotropes ... comparison #table #pharmacology
SCAI Pyramid of Cardiogenic Shock Classification
E - Extremis - A patient experiencing cardiac arrest with ongoing
of Cardiogenic Shock ... Classification ... C - Classic - A ... intervention (inotrope ... #Classification
Antiarrhythmics - Vaughan Williams Classification:
CLASS 1 - Sodium Channel Blockers:
 • MOA: Block fast Na+ channels
Vaughan Williams Classification ... force (negative inotropy ... Vaughan #Williams #Pharmacology ... #Classification ... #Classes #pathophysiology
Antiarrhythmics Pharmacology Summary
Cardiac Conduction Phases:
Phase 0 - Ventricular Depolarization:
 • Na+ channels open leading to a
Antiarrhythmics Pharmacology ... Vaughan Williams Classification ... force (negative inotropy ... #Classification ... #Classes #pathophysiology
Causes of Lactate Elevation, Lactic Acidosis - Differential Diagnosis

The most common causes of hyperlactatemia are usually:
undifferentiated shock ... is in impending shock ... perfusion - shock ... vasopressors, or inotropes ... #typea #typeb #classification
Lymphomas and Lymphoproliferative Disorders - Differential Diagnosis Algorithm
Hodgkin Lymphoma ~40% - Characteristic For Reed-Sternberg (RS) Cells
Differential Diagnosis Algorithm ... are present • Classic ... Lymphoproliferative #Disorders #Classification ... #pathophysiology ... #differential #algorithm
It is important to recognize Acute Decompensated Heart Failure (ADHF) as more than just simply a
essentially Cardiogenic Shock ... patients need inotrope ... #differential #algorithm ... icu #clinical #pharmacology