13 results
CNS Infection in HIV / AIDS - Differential Diagnosis Framework

Principles of HIV-Associated CNS Opportunistic Infections:
 •
CNS Infection in ... when cART is started ... should be based on clinical ... Imaging: - MRI ... effect/Edema • EBV
Transverse Myelitis Overview

Focal inflammatory disorder of the spinal cord resulting in rapid onset of weakness, sensory
that results in CNS ... Transverse Myelitis - Clinical ... bouts of HTN Diagnostic ... Transverse Myelitis Diagnosis ... Brucellosis - Dengue, EBV
CNS Infections - Viral Encephalitis and Bacterial Meningitis - Differential Diagnosis Framework

Viral Encephalitis:
MCC: Enteroviruses (e.g., coxsackievirus
CNS Infections - ... virus • CMV • EBV ... • Common clinical ... Symptoms: • Acute ... Singh @rav7ks #CNS
Guillain-Barré Syndrome (GBS)
Acute autoimmune demyelinating polyradiculoneuropathy that presents with rapidly progressive flaccid weakness
Epidemiology:
 • Incidence: 1
Syndrome (GBS) Acute ... transplantation CLINICAL ... demyelinating or axonal • MRI ... - Spinal MRI may ... specific therapy, the clinician
HIV-Associated Neurocognitive Disorder (HAND)

Definition:
HIV-Associated Neurocognitive disorders categories:
• Asymptomatic neurocognitive impairment
• Mild neurocognitive impairment
• HIV dementia

Pathophysiology:
HIV frequently
and infects the CNS ... early stages of infection ... Diagnosis: MRI ... : • Increased CSF ... : The clinical
Guillain-Barre Syndrome - Summary

Acute AIDP that presents with rapidly progressive flaccid weakness

Epidemiology:
 • 1-2 cases/100,000 per
Syndrome - Summary Acute ... response preceding infection ... - HIV, CMV, EBV ... Guillain-Barre Clinical ... axonal form • MRI
Mycoses

HISTOPLASMOSIS
• Inhalation of conidia → Yeast → travel to lymph nodes → spread in body
• Bird
presents with acute ... has five major clinical ... fungal stain of clinical ... especially the CNS ... MC: CNS CSF: •
One and a Half Syndrome on Physical Exam

This 28 year old patient presented to clinic with
patient presented to clinic ... MRI was ordered ... the hospital, diagnosed ... with MS, and started ... Half #Syndrome #PhysicalExam
Vasculitis - Differential Diagnosis Framework

When to Consider Vasculitis:
• Purpura, ischemic skin lesions
• Mononeuritis multiplex
• Hematuria, proteinuria,
- Differential Diagnosis ... diseases to exclude are ... oligoclonal bands • MRI ... pain and GN Anti-GBM ... chorioretinitis, CNS
Cryptococcal meningitis on T2 MRI
30 M from sub-Saharan Africa presents w/ progressive Headache x1 mo, +neck
meningitis on T2 MRI ... Diagnosis? ... low glucose) CNS ... drained at time of diagnosis ... #Brain #clinical