16 results
Approach to Joint Pain - Arthritis Differential Diagnosis Framework

Inflammatory Versus Noninflammatory Pain
 • Is it inflammatory
the time course (acute ... Crystal induced (Gout ... - Autoimmune Rheumatologic ... fever • Lyme • Gout ... Diagnosis #MSK #rheumatology
Gout - Diagnosis and Management Summary

3 Conditions for Gout to Manifest:
1. Hyperuricemia
2. Monosodium urate deposition in
and Management ... sex • Metabolic syndrome ... swelling, significant pain ... #diagnosis #management ... #treatment #rheumatology
Approach to Joint Pain - Diagnostic Framework

1) Chronicity
2) Inflammatory vs Non-Inflammatory
3) Number of Joints Involved

1) Chronicity:
Approach to Joint Pain ... Like in this case ... #Joint #Pain #MSK ... #rheumatology # ... approach #workup
Adult-Onset Still's Disease (AOSD)
Rare inflammatory disorder of unknown etiology, difficult to diagnose because of heterogenous presentation.
Disease (AOSD) Rare ... Must rule out other ... NSAIDs, steroids (acutely ... Disease #AOSD #rheumatology ... #diagnosis #management
CPPD vs Gout

== CPPD == 

Think About CPPD When:
 • Self-limited synovitis after surgery/trauma (> 65
onset of swelling, pain ... Chronic CPP Crystal ... • Metabolic syndrome ... swelling, significant pain ... #Comparison #rheumatology
SAPHO Syndrome Summary

What?
SAPHO syndrome is a rare chronic inflammatory disorder of bone, joint, and skin characterized
a rare chronic ... lesions + Rheumatic pain ... diagnosis • Rule out ... #Rheumatology # ... diagnosis #management
Leukemias Overview: ALL, CML, AML, APML, CLL

Acute leukemias > 20% blasts in the peripheral blood smear
, APML, CLL Acute ... develop leukostasis syndrome ... • Tumor lysis syndrome ... When Cancer Cells are ... #Leukemia #Hematology
Differentiation Syndrome in APML
Epidemiology:
 • Incidence: common in APL (2-48% depending on the study)
 • Triggers:
Differentiation Syndrome ... effusions, weight gain ... • Supportive Care ... APML #diagnosis #management ... #hematology #oncology
Chronic Lymphocytic Leukemia - Summary

Cancer affecting lymphocytes/Mature B cell neoplasm
 • Lymphocytes accumulate in large numbers
Chronic Lymphocytic ... large numbers and are ... ’s lymphoma or acute ... Leukemia #diagnosis #workup ... #oncology #hematology
Hemophagocytic Lymphohistiocytosis (HLH)
Definition: Overwhelming clinical syndrome associated with excessive macrophage activation and cytokine storm due to
Overwhelming clinical syndrome ... presents as an acute ... the main goal of ... Lymphohistiocytosis #diagnosis #management ... #treatment #hematology