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differential causes abnormal aptt management prolonged anticoagulant anticoagulation apixaban bleeding bruising cascade clot comparison dabigatran dic disseminated edoxaban hemophilia hemostasis
Disseminated Intravascular Coagulation (DIC) Overview Increased Clotting and Consumption of Clotting Factors Findings: • Bleeding • Recent history
• Prolonged PT ... Fibrinogen: ↓ • PT ... #diagnosis #causes ... #treatment #management ... #hematology
Causes of Abnormal PT and/or aPTT Prolonged Prothrombin Time (PT) 1. Acquired deficiency of FVII
(exceptionally rare ... intravascular coagulation ... Prolonged #Causes #diagnosis ... #differential #hematology ... #coagulation
Differential Diagnosis for a Prolonged PT and aPTT If the PT and the aPTT are both prolonged,
Differential Diagnosis ... for a Prolonged PT ... Prolonged #Causes #diagnosis ... #differential #hematology ... #coagulation
The coagulation cascade is shown, separated into different phases with their endogenous and pharmacological inhibitors shown.
The coagulation ... #Coagulation #Cascade ... thrombin #clot #PT ... #PTT #diagnosis ... #models #hematology
Hemophilia - Diagnosis and Management Diagnosis: • Consistent bleeding history (unless screening for disease in family members
mild cases) • PT ... multidisciplinary care ... by a hemophilia treatment ... #Management #treatment ... #hematology
Bleeding and Bruising - Disorders of Hemostasis - Differential Diagnosis Framework == Quantitative or Qualitative defect in
- Differential Diagnosis ... inhibitor of a coagulation ... intravascular coagulation ... #Differential #Diagnosis ... #Hematology
Scleroderma Like Conditions - Differential Diagnosis Eosinophilic Fasciitis: - Orange peel induration (peau d'orange) of proximal extremities
- Differential Diagnosis ... glucocorticoids are ... the mainstay of treatment ... #comparison #table ... #dermatology
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