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dermatology differential oncology rheumatology treatment algorithm clinical hemophagocytic hepatology hlh immunology leukemia lymphohistiocytosis skin adrenal allergy anemia calcium cancer causes
Differentiation Syndrome in APML Epidemiology: • Incidence: common in APL (2-48% depending on the study) • Triggers:
Differentiation Syndrome ... • Supportive Care ... Differentiation #Syndrome ... #APML #diagnosis ... #management #hematology
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes Intravascular Hemolysis: • Mechanical Trauma (Microangiopathic hemolytic anemia):
Diagnostic Framework ... • Mechanical Trauma ... ) - HELLP syndrome ... lactam antibiotics are ... #hematology #anemia
Leukemias Overview: ALL, CML, AML, APML, CLL Acute leukemias > 20% blasts in the peripheral blood smear
extramedullary disease ... develop leukostasis syndrome ... • Tumor lysis syndrome ... #Leukemia #Hematology ... #Oncology #Diagnosis
Common Variable Immunodeficiency (CVID) What? CVID: Immunodeficiency disorder with hypogammaglobulinemia -> increased infection risk secondary to impaired B-cell
and M panel Management ... : • Nephrotic syndrome ... (Epstein-Barr syndrome ... hypogammaglobulinemia #immunology #hematology ... #diagnosis #management
Adrenal Insufficiency - Diagnosis and Management Summary Primary Adrenal Insufficiency: Most Common Cause in the US: Autoimmune Adrenalitis Other
and Management ... or metastatic disease ... , infiltrative diseases ... hypophysitis, Sheehan's syndrome ... #Management #Endocrinology
Polycythemia Vera (PV) - Diagnosis and Management Summary Diagnostic Criteria: • Elevated hemoglobin and/or hematocrit AND •
and Management ... transformation into AML ... von Willebrand disease ... #Management #Summary ... #treatment #hematology
Hepatopulmonary Syndrome - Diagnosis and Management Summary A defect in arterial oxygenation due to a gas exchange
Hepatopulmonary Syndrome ... Supportive care ... hepatopulmonary #syndrome ... #diagnosis #management ... #treatment #hepatology
Hemophagocytic Lymphohistiocytosis (HLH) Definition: Overwhelming clinical syndrome associated with excessive macrophage activation and cytokine storm due to
Overwhelming clinical syndrome ... age, however the disease ... insulting agent are ... #management #treatment ... #hematology
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
are a group of ... transformation to AML ... Myeloproliferative Disease ... progression to AML ... #diagnosis #hematology
Acute Liver Injury - Differential Diagnosis Algorithm Vascular Causes of Acute Liver Injury: • Hepatic vein:
- Differential Diagnosis ... vein: Budd-chiari syndrome ... , CMV, VZV • Trauma ... NT) - If both are ... • Gilbert's syndrome
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