4 results
Clozapine Toxicology
Clozapine is an atypical antipsychotic most often reserved for use in patients who have treatment-resistant
Clozapine Toxicology ... atypical antipsychotic ... patients who have treatment-resistant ... #Toxicology #Toxicity ... #Diagnosis #Pharmacology
Second Generation Antipsychotics: Mechanisms and Side Effects
(Atypical Anti-Psychotics) - Examples: Clozapine, Olanzapine, Quetiapine, Risperidone, Zotepine, Paliperidone,
Second Generation Antipsychotics ... binding affinities are ... considered 2nd line treatment ... Mechanism unknown #AntiPsychotics ... #SideEffects #pharmacology
Drug-Induced Prolonged QTc

QTc >500ms is an independent risk factor for developing Torsades des Pointes (TdP)
Drugs causing
Quinidine, Sotalol • Antipsychotics ... Chlorpromazine, Clozapine ... Prolonged #QTc #Toxicity ... #Toxicology #Pharmacology
Methotrexate Toxicology 

Intravenous leucovorin (folinic acid) treatment serves as a cofactor necessary for synthesis of thymidylate
Methotrexate Toxicology ... (folinic acid) treatment ... evidence of marrow toxicity ... #Toxicity #Management ... #Pharmacology