15 results
Approach to Thrombocytosis - Elevated Platelet Count - Differential Diagnosis Algorithm

Peripheral Smear concerning for malignancy?
Rebound effect from treatment ... Inflammatory Conditions: Rheumatologic ... Vasculitides, IBD, Celiac disease ... Kawasaki, Nephrotic syndrome ... infarction, Severe trauma
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes
Intravascular Hemolysis:
 • Mechanical Trauma (Microangiopathic hemolytic anemia):
Diagnostic Framework ... • Mechanical Trauma ... ) - HELLP syndrome ... lactam antibiotics are ... #hematology #anemia
Hemophagocytic Lymphohistiocytosis (HLH)
Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
adenopathies, confusion ... • Autoimmune diseases ... Unknown cause Treatment ... #management #treatment ... #summary #rheumatology
Hemophagocytic Lymphohistiocytosis (HLH)
Definition: Overwhelming clinical syndrome associated with excessive macrophage activation and cytokine storm due to
Overwhelming clinical syndrome ... age, however the disease ... • Bicytopenia Treatment ... #management #treatment ... #hematology
Causes of Lactate Elevation, Lactic Acidosis - Differential Diagnosis

The most common causes of hyperlactatemia are usually:
presentations and disease ... / hypoxemia -> focus ... perfusion - shock->treatments ... before beginning treatment ... - Compartment syndrome
Blurry Vision - Differential Diagnosis Framework

Anatomical Approach to Eye Disease:
1. Lids/Lashes
2. Extraocular Muscles/Motility
3. Conjunctiva/Sclera
4. Cornea
5. Anterior
- Differential Diagnosis ... Approach to Eye Disease ... Trauma Cornea ... Malignancy • Concussion ... • Sjögren’s syndrome
Myelodysplastic Syndromes (MDS)

What?
Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
Myeloproliferative Disease ... factor (GCSF) treatments ... marrow studies Treatment ... Immunosuppressive treatment ... #diagnosis #hematology
Sjogren's Syndrome Overview

Epidemiology:
• F > M: 9:1
• 5-6th Decades (can be any age)

Autoimmune exocrinopathy multisystemic disease
Diagnosis: • Dry ... renal tubular acidosis ... Adenocarcinoma Treatment ... #Rheumatology # ... Diagnosis #Management
SAPHO Syndrome Summary

What?
SAPHO syndrome is a rare chronic inflammatory disorder of bone, joint, and skin characterized
a rare chronic ... and lower jaw Treatment ... osteoarticular and skin disease ... #Rheumatology # ... diagnosis #management
Chronic Lymphocytic Leukemia - Summary

Cancer affecting lymphocytes/Mature B cell neoplasm
 • Lymphocytes accumulate in large numbers
large numbers and are ... phenomenon CLL Diagnosis ... cells can indicate disease ... microglobulin Treatment ... • Richter’s Syndrome