8 results
Systemic Sclerosis (Scleroderma)
Multi-system autoimmune disease characterized by vasculopathy and progressive fibrosis of skin and internal organs
3
Multi-system autoimmune disease ... elbows/wrists and knees ... skin thickening Signs ... and Symptoms: ... #workup
Chronic Lymphocytic Leukemia - Summary

Cancer affecting lymphocytes/Mature B cell neoplasm
 • Lymphocytes accumulate in large numbers
adults in the west ... with no early symptoms ... Physical Exam/Signs ... cells can indicate disease ... Leukemia #diagnosis #workup
Lyme Disease: Early and Late Clinical manifestations
Stage 1. Localized
 • EM appears 7-14 days at the
Lyme Disease: Early ... SSX (lymphocytic ... Large joints (knees ... #diagnosis #signs ... #symptoms
Primary Biliary Cirrhosis (PBC) - Summary

PBC Epidemiology:
 • Female:Male 9:1
 • Common European descent
 • Age:
Pathophysiology: • T lymphocyte ... failure PBC Signs ... and Symptoms: ... cholestasis, Primary sclerosis ... #hepatology
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup
History:
 - Prior platelet count, family
Diagnosis and Workup ... K), H. pylori test ... (GI symptoms/endemic ... (CVID, WAS), (neurologic ... #hematology
Transverse Myelitis Overview

Focal inflammatory disorder of the spinal cord resulting in rapid onset of weakness, sensory
• Bilateral signs ... and/or symptoms ... Pleocytosis: Mild lymphocytic ... negative, MOG-IgG test ... diagnosis #management #neurology
Hodgkin's Lymphoma Overview

Hodgkin's lymphoma (HL) is an uncommon hematological malignancy arising from mature B cells. It
ingestion • B symptoms ... subtypes: - Nodular sclerosis ... Hodgkin Lymphoma Workup ... number of sites of disease ... classification #hematology
Vasculitis - Differential Diagnosis Framework

When to Consider Vasculitis:
• Purpura, ischemic skin lesions
• Mononeuritis multiplex
• Hematuria, proteinuria,
Presentation: Systemic Symptoms ... , particularly scleritis ... purpura: Strong sign ... • Progressive symptoms ... elevated protein, lymphocytic