37 results
Classification of Tumor Lysis Syndrome (TLS) and Treatment of Metabolic Abnormalities of TLS
Laboratory TLS:
 • Uric
of Tumor Lysis Syndrome ... (TLS) and Treatment ... Calcium ≤ 7.0 mg/dL Clinical ... arrhythmia • Seizure ... #TumorLysis #Syndrome
The rationale for aggressive treatment of generalized status epilepticus was described previously here.  In short,
for aggressive treatment ... epilepticus which may cause ... epilepticus may cause ... aspiration, hyperkalemia ... #Management #Neurology
Causes of Seizures - Differential Diagnosis Algorithm
Unprovoked - Epilepsy:
 • Focal: Simple, Complex
 • Generalized: Absence,
Causes of Seizures ... vasoconstriction syndrome ... Hypomagnesemia, Hypocalcemia ... Diagnosis #Algorithm #Causes ... #neurology
Rhabdomyolysis - Differential Diagnosis Framework and Management Summary

Causes of Rhabdomyolysis:
 • Trauma:
	- Immobilization
	- Crush injury
	- Compartment
Management Summary Causes ... exertion/training - Seizures ... Dermatomyositis Clinical ... Diagnosis #Management #causes ... #treatment #nephrology
Causes of Hypokalemia
Transcellular Shifts:
 - Alkalosis, Increased plasma insulin (treatment of diabetic ketoacidosis), ß-Adrenergic agonists, Hypokalemic
Causes of Hypokalemia ... plasma insulin (treatment ... use), Gitelman's syndrome ... #Causes #differential ... #diagnosis #nephrology
Posterior Reversible Encephalopathy Syndrome (PRES) Overview

Clinico-Radiological Syndrome, characterized by:
 • Headache
 • Seizures
 • Altered mental
may precede the neurologic ... epilepticus Treatment ... the underlying cause ... • Treatment of ... with AEDs until cause
Clinical manifestations of anaphylaxis. 
Neurological (<15%): Dizziness, syncope, seizures, Confusion, impending doom. headache
Angioedema: Lips, tongue, orbit,
Clinical manifestations ... Dizziness, syncope, seizures ... ischemia, arrhythmia, hypovolemia ... arrest, Kounis syndrome ... arrest GI (>40%): Nausea
Leukostasis vs Tumor Lysis Syndrome
Leukostasis:
 • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
high WBC count cause ... organ damage • Treatment ... dysrhythmias, seizures ... hydration - Hyperkalemia ... treatment (no calcium
Rhabdomyolysis - Differential Diagnosis and Management Summary

Trauma:
 • Immobilization, Crush iniury, Compartment syndrome, Electrical injury
Exertional:
 •
iniury, Compartment syndrome ... exertion/training, Seizures ... Dialysis for severe hyperkalemia ... Management #Summary #causes ... #treatment
Causes of Secondary Hypertension - Workup and Differential Diagnosis
Approach (when evaluation should be done):
1. Severe or
heart failure, neurologic ... disorders including hypokalemia ... 109 mm Hg) with clinical ... hormonal excess or hypokalaemia ... Neurologic disorders