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management differential disease hematology myositis symptoms workup abnormal agglutinin algorithm anemia arthritis behcet bronchiectasis celiac chronic cll cold dermatitis enzymes
Autoimmune Myositis Necrotizing myopathy is associated with higher CK levels, greater level of muscle weakness, less systemic
Autoimmune Myositis ... , holster sign, ... anti-synthetase syndrome ... after 2 years of treatment ... #rheumatology
Myasthenia Gravis Overview Myasthenia Gravis is an autoimmune disorder of the postsynaptic neuromuscular junction. Ab to
Myasthenia Gravis is an autoimmune ... Bedside: ice pack test ... /Edrophonium test ... - Cogan sign ... - Peek sign 2.
Systemic Sclerosis (Scleroderma) Multi-system autoimmune disease characterized by vasculopathy and progressive fibrosis of skin and internal organs 3
Multi-system autoimmune ... elbows/wrists and knees ... Scleroderma #SSc #rheumatology ... #diagnosis #signs ... #symptoms #testing
Abnormal liver function tests algorithm. This figure details the initial response to abnormal liver blood tests.
clinical symptoms/signs ... presence of metabolic syndrome ... Areas of diagnostic ... decision for repeat testing ... mellitus; USS, ultrasound
Hemophagocytic Lymphohistiocytosis (HLH) Definition: Overwhelming clinical syndrome associated with excessive macrophage activation and cytokine storm due to
Overwhelming clinical syndrome ... : HLH signs and ... • Bicytopenia Treatment ... #management #treatment ... #hematology
Cold Agglutinin Disease 3 Types of Cold Sensitive Antibodies: 1. Cold Agglutinins (CAD) 2. Donath-Landsteiner
Cold Agglutinin Syndrome ... Viral infection, autoimmune ... Positive Coombs testing ... CLL (older) • Autoimmune ... test #cold #
Behçet's Syndrome Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy Epidemiology: • Young
Positive pathergy test ... is a skin prick test ... Arthritis, AS Treatment ... #signs #symptoms ... #rheumatology #
Rheumatoid Arthritis Summary Overview: chronic, inflammatory symmetric polyarthritis involving small joints of hands/feet, knees, shoulders Signs & Symptoms:
of hands/feet, knees ... , shoulders Signs ... narrowing) • Ultrasound ... exam and imaging Treatment ... #management #rheumatology
Bronchiectasis - Summary What? • Bronchiectasis is derived from the Greek words bronckos meaning airway and ectasis meaning
• Mounier-Kuhn syndrome ... Nasal polyps and signs ... parenchyma Diagnosis ... mycobacteria Treatment ... #differential #diagnosis
Gout - Diagnosis and Management Summary 3 Conditions for Gout to Manifest: 1. Hyperuricemia 2. Monosodium urate deposition in
sex • Metabolic syndrome ... forefoot, ankles, knees ... Synovial Fluid Testing ... not possible • Ultrasound ... #rheumatology
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