10 results
Vasculitis and Vasculitides - Differential Diagnosis Framework

When to Consider Vasculitis:
 • Purpura, ischemic skin lesions
 •
- GI tract: abdominal ... Presentation - Systemic Symptoms ... purpura: strong sign ... Supply gut -> abdominal ... LFT • ESR • ANA
Behçet's Syndrome
Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy
Epidemiology:
 • Young
meningitis), MCC CNS symptoms ... • Nonsurgical abdominal ... Glucocorticoids 5-ASA ... Syndrome #diagnosis #management ... #signs #symptoms
Vasculitis - Differential Diagnosis Framework

When to Consider Vasculitis:
• Purpura, ischemic skin lesions
• Mononeuritis multiplex
• Hematuria, proteinuria,
Presentation: Systemic Symptoms ... purpura: Strong sign ... multiplex • GI tract: Abdominal ... • Progressive symptoms ... gut involvement, abdominal
Clinical Features of Systemic Lupus (SLE)
General: Fever (50%), Depression, Fatigue (75%), Weight loss (50%)
Eye: Sjögrens (15%)
Skin
Butterfly rash, Vasculitis ... effusion, Restrictive lung ... of hip (rare), Arthritis ... erythematosus #signs ... #symptoms #diagnosis
Rheumatoid arthritis (RA): Extra-articular manifestations
Skin: 
 • Inflammation of skin (esp. over areas of stress) forms
Rheumatoid arthritis ... blood vessels (vasculitis ... disease/pulmonary ... pathophysiology #signs ... #symptoms #diagnosis
Rheumatoid Arthritis - Signs and Symptoms
 • Ocular: Keratoconjunctivitis sicca, Episcleritis, Scleritis, Scleromalacia perforans
 • Pulmonary:
- Signs and Symptoms ... Scleromalacia perforans • Pulmonary ... : Parenchymal lung ... Vascular: Rheumatoid vasculitis ... #RA #Signs #Symptoms
Pulmonary Renal Syndromes - OnePager Summary
Autoimmune ANCA vasculitis (AAV): GPA (granulomatous with polyangiitis), EGPA (eosinophilic granulomatosis
Autoimmune ANCA vasculitis ... palpable purpura 2/2 vasculitis ... or serologies + symptoms ... sparing of the lung ... differential #diagnosis #management
Giant cell arteritis (GCA)

Giant cell arteritis (GCA) definition: Most common systemic inflammatory vasculitis in older adults
systemic inflammatory vasculitis ... systemic sx + signs ... GCA #Temporal #Signs ... #Symptoms #Diagnosis ... #Management
Sarcoidosis - Diagnosis and Management Summary
Epidemiology
1) High incidence in Scandinavian countries (11-24 cases per 100,000 individuals
Diagnosis and Management ... granulomas within the lungs ... Pulmonary: dyspnea ... Extrapulmonary: ankle arthritis ... #Signs #Symptoms
Mycoses

HISTOPLASMOSIS
• Inhalation of conidia → Yeast → travel to lymph nodes → spread in body
• Bird
3) Abdominal, ... the lungs and becomes ... Meningitis, septic arthritis ... nails, bronchi, lungs ... Fungal #Diagnosis #Management