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differential management infectiousdiseases activetb aids latenttb tb treatment tuberculosis antibiotic cns emergencies failure hemeonc inflammatory iris mycoses myelitis oncologic oncology
CNS Infection in HIV / AIDS - Differential Diagnosis Framework Principles of HIV-Associated CNS Opportunistic Infections: •
CNS Infection in ... Diagnosis Framework ... required until immune ... Infections in HIV ... #CNS #Infections
Causes of Antibiotic Failure - Differential Diagnosis Framework Diagnosis: • Non-Infectious: Malignant, Autoimmune, Drug-related (NMS, serotonin syndrome,
bacteria: Viral, Fungal ... Tissue penetration (CNS ... , prostate, ocular ... (daptomycin in lungs ... : IV catheter (CLABSI
Tuberculosis Overview 10 million new M. tuberculosis infections/year Facultative intracellular rod-shaped bacteria Multidrug-resistant tuberculosis (MDR-TB) accounts for 4.6% of
(NTM) • Fungal ... Progression: (+) Immune ... rest LTBI (-) Immune ... Tuberculosis Diagnosis ... Tuberculosis #TB #Diagnosis
Tuberculosis Overview 10 million new M. tuberculosis infections/year Facultative intracellular rod-shaped bacteria Multidrug-resistant tuberculosis (MDR-TB) accounts for 4.6% of
(NTM) • Fungal ... Progression: (+) Immune ... rest LTBI (-) Immune ... Tuberculosis Diagnosis ... Tuberculosis #TB #Diagnosis
Lung Infections in HIV - Differential Diagnosis Framework Disease by CD4 Count: Any CD4 Count: • Mycobacterium tuberculosis,
Lung Infections ... Diagnosis Framework ... Pseudomonas FUNGAL ... lymphadenopathy, • Abdominal ... #Infections #HIV
Mycoses HISTOPLASMOSIS • Inhalation of conidia → Yeast → travel to lymph nodes → spread in body • Bird
Pulmonary 3) Abdominal ... MC: CNS CSF: • ... osteoarticular, pulmonary, ocular ... change in the lungs ... nails, bronchi, lungs
Vasculitis - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions • Mononeuritis multiplex • Hematuria, proteinuria,
- Differential Diagnosis ... affects the skin, neurologic ... multiplex • GI tract: Abdominal ... cognitive impairment, neurologic ... gut involvement, abdominal
Immune Reconstitution Inflammatory Syndrome - Overview of IRIS What Is IRIS? • A state of hyperinflammatory response that
a decrease in HIV ... increase in CD4+ cells ... pleural effusions, CNS ... skin lesions, ocular ... Zoster flare, ocular
Transverse Myelitis Overview Focal inflammatory disorder of the spinal cord resulting in rapid onset of weakness, sensory
activation of an immune ... that results in CNS ... mediated disease • Immune ... simplex virus, HIV ... #management #neurology
Summary of Oncologic Emergencies Neutropenic fever: - Fever + ANC < 500 → start cefepime ± vancomycin (if
if SSTI or port infection ... CT abdomen if abdominal ... pain; full infectious ... > 4 days → add fungal ... Oncology #HemeOnc #Diagnosis
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