10 results
HIV-Associated Neurocognitive Disorder (HAND)

Definition:
HIV-Associated Neurocognitive disorders categories:
• Asymptomatic neurocognitive impairment
• Mild neurocognitive impairment
• HIV dementia

Pathophysiology:
HIV frequently
early stages of infection ... cells in the CNS ... Diagnosis: MRI ... The clinical syndrome ... dementia #AIDS #Neurology
Behçet's Syndrome
Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy
Epidemiology:
 • Young
ulceration • Ocular ... skin injury) • Neurologic ... ) Differential Diagnosis ... • Nonsurgical abdominal ... #diagnosis #management
Vasculitis - Differential Diagnosis Framework

When to Consider Vasculitis:
• Purpura, ischemic skin lesions
• Mononeuritis multiplex
• Hematuria, proteinuria,
- Differential Diagnosis ... affects the skin, neurologic ... multiplex • GI tract: Abdominal ... cognitive impairment, neurologic ... gut involvement, abdominal
Rhabdomyolysis - Differential Diagnosis Framework and Management Summary

Causes of Rhabdomyolysis:
 • Trauma:
	- Immobilization
	- Crush injury
	- Compartment
- Differential Diagnosis ... Framework and Management ... Statins - ETOH - Infection ... - Viral (HIV, Influenza ... Tachycardia - N/V - Abdominal
Guillain-Barre Syndrome - Summary

Acute AIDP that presents with rapidly progressive flaccid weakness

Epidemiology:
 • 1-2 cases/100,000 per
response preceding infection ... Campylobacter jejuni - HIV ... Life threatening labile ... #diagnosis #management ... #treatment #neurology
Immune Reconstitution Inflammatory Syndrome - Overview of IRIS

What Is IRIS?
	• A state of hyperinflammatory response that
Reconstitution Inflammatory Syndrome ... skin lesions, ocular ... Zoster flare, ocular ... #Inflammatory #Syndrome ... #Management
Lung Infections in HIV - Differential Diagnosis Framework

Disease by CD4 Count:
Any CD4 Count:
 • Mycobacterium tuberculosis,
Lung Infections ... Diagnosis Framework ... Pneumonia: • 3 syndromes ... of a "flu-like syndrome ... lymphadenopathy, • Abdominal
Transverse Myelitis Overview

Focal inflammatory disorder of the spinal cord resulting in rapid onset of weakness, sensory
that results in CNS ... bouts of HTN Diagnostic ... Pleocytosis > 100 cells ... simplex virus, HIV ... #management #neurology
Sjogren's Syndrome Overview

Epidemiology:
• F > M: 9:1
• 5-6th Decades (can be any age)

Autoimmune exocrinopathy multisystemic disease
Diagnosis: • Dry ... gland) biopsy • Ocular ... Can cause TYPE IV ... RTA, TYPE I RTA Diagnosis ... #Management
Mycoses

HISTOPLASMOSIS
• Inhalation of conidia → Yeast → travel to lymph nodes → spread in body
• Bird
Pulmonary 3) Abdominal ... especially the CNS ... MC: CNS CSF: • ... osteoarticular, pulmonary, ocular ... #Management #Infections