11 results
Growth Hormone Excess - Pathogenesis and clinical findings
 • Acromegaly and gigantism share the same pathophysiology
• Other rare causes ... hemianopsia IGF-1 ... Overproduction #diagnosis #signs ... #symptoms #endocrinology ... #pathophysiology
Leukostasis vs Tumor Lysis Syndrome
Leukostasis:
 • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
Leukostasis: • Pathophysiology ... high WBC count cause ... WBC >100k, + lab signs ... proliferation rate ... diagnosis #management #hematology
Pituitary Mass Effects - Pathogenesis and Clinical Findings
 • Pituitary turnors are almost always a benign
approximately 1 ... adenomas that require treatment ... Signs / Symptoms ... #SideEffects #endocrinology ... mnemonic #GLFTAP #pathophysiology
Primary Biliary Cirrhosis (PBC) - Summary

PBC Epidemiology:
 • Female:Male 9:1
 • Common European descent
 • Age:
Female:Male 9:1 ... 65 years PBC Pathophysiology ... intralobular bile ducts causes ... failure PBC Signs ... • Jaundice (later
Heat Illnesses and Heat Stroke - Differential Diagnosis Framework

Heat Cramps:
 • Muscle pain or spasm -
Collapse: • Pathophysiology ... → Syncope • Signs ... - Athlete - difficulty ... Multi-system illness: 1. ... differential #diagnosis #causes
Giant cell arteritis (GCA)

Giant cell arteritis (GCA) definition: Most common systemic inflammatory vasculitis in older adults
systemic sx + signs ... identifies 85 to 95% of cases ... of the steroid treatment ... Treatment of GCA ... GCA #Temporal #Signs
Amyotrophic Lateral Sclerosis (ALS) Summary
ALS: combination of the clinical examination finding of amyotrophy with the pathologic
lateral sclerosis Pathophysiology ... - Causes progressive ... ALS involves: (1) ... features developing later ... diagnosis column Treatment
Polymyalgia Rheumatica (PMR) Diagnosis and Management Summary

WHAT?
 • Polymyalgia rheumatica (PMR) is a common systemic inflammatory
disease of unknown cause ... commonly describe difficulty ... sedimentation rate ... TREATMENT: • The ... mainstay of treatment
Transverse Myelitis Overview

Focal inflammatory disorder of the spinal cord resulting in rapid onset of weakness, sensory
monophasic Pathophysiology ... varying degrees of: 1. ... Hyperreflexia develops later ... • Bilateral signs ... • Infectious causes
Hemophagocytic Lymphohistiocytosis (HLH)

High mortality without prompt recognition and management. HLH is a critical diagnostic consideration in
dysfunction. 1. ... hyperinflammatory syndrome caused ... the trigger is difficult ... Presentation • Common Signs ... Pathophysiology