10 results
Monoclonal Gammopathy of Clinical Significance (MGUS) - Differential Diagnosis

Neurologic-Centered:
 (+) Systemic Features: POEMS, AL amyloid, Cryoglobulinemia
Diagnosis Neurologic-Centered ... DADS-M, Sporadic, late-onset ... capillary leak syndrome ... • Schnitzler syndrome ... #Diagnosis #hematology
Leukostasis vs Tumor Lysis Syndrome
Leukostasis:
 • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
Leukostasis: • Pathophysiology ... WBC >100k, + lab signs ... : • Pathophysiology ... proliferation rate ... #TLS #diagnosis
Hypochloremia - Differential Diagnosis Algorithm

Cause - Decreased Intake:
 • Low salt in diet
 • Exclusive D5W
Hypochloremia - Differential ... Diagnosis Algorithm ... - Gitelman SIGNS ... #Pathophysiology ... #Nephrology #Chloride
Peri-operative Hyperthermia - Guidelines for Crises in Anaesthesia
If prolonged or ≥ 39 C this is a
hyperthermia crisis (late ... sign) (→ 3-8) ... Phaeochromocytoma Neurologic ... #Hyperthermia #Differential ... Anesthesia #Checklist #Diagnosis
Primary Biliary Cirrhosis (PBC) - Summary

PBC Epidemiology:
 • Female:Male 9:1
 • Common European descent
 • Age:
65 years PBC Pathophysiology ... failure PBC Signs ... • Jaundice (later ... bile ducts Differential ... #workup #hepatology
Paraproteinemias

Entities That Can Feature A Monoclonal Protein/M Component:
• MM
• WM
• MGUS
• MGCS
• MGRS
• Splenic Marginal Zone
et diutinum Neurologic ... neuropathy) • Systemic late-onset ... Paraproteinemias #Hematology ... #Monoclonal #Differential ... #Diagnosis #Oncology
Amyotrophic Lateral Sclerosis (ALS) Summary
ALS: combination of the clinical examination finding of amyotrophy with the pathologic
lateral sclerosis Pathophysiology ... of UMN and LMN signs ... features developing later ... conditions listed in differential ... Lateral #Sclerosis #neurology
Aortoenteric Fistula - Diagnosis and Management Summary
Epidemiology:
• Uncommon but life-threatening
• Most common site of bowel connection
duodenum Clinical Signs ... • Should be on differential ... that precedes a later ... Pathophysiology: ... - CMC IM Residency
The Neurological Evaluation of a Comatose Patient

Definition:
 • Coma: a state of unresponsiveness; the absence of
consciousness Differential ... • Mutism Pathophysiology ... • Examine for signs ... caseyalbin #PhysicalExam ... #neurology #comatose
Transverse Myelitis Overview

Focal inflammatory disorder of the spinal cord resulting in rapid onset of weakness, sensory
monophasic Pathophysiology ... Hyperreflexia develops later ... • Bilateral signs ... #management #neurology ... #differential