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management comparison differential hyperglycemic ketoacidosis algorithm diabeticketoacidosis disorders hyperosmolar ketosis aniongap crisis criticalcare ddxof dm2 edka em endo foamed fungal
Ketosis Disorders - Comparison Table • Starvation Ketosis • Alcoholic Ketoacidosis (AKA) • Diabetic Ketoacidosis (DKA)
) • Diabetic Ketoacidosis ... Hyperosmolar State (HHS ... ) • DKA/HHS Overlap ... #differential #diagnosis ... #management #endocrinology
Pathophysiology of Diabetic Ketoacidosis (DKA) and Hyperglycemic Hyperosmolar Syndrome (HHS) Absolute Insulin deficit: - Type I DM:
Pathophysiology ... of Diabetic Ketoacidosis ... #hhs #pathophysiology ... #comparison #endocrinology ... #diabetes #diabetic
Ketosis Disorders Ketone bodies are a normal metabolic energy source. Excessive unregulated production of ketones, often accompanied
• Diabetic ketoacidosis ... • DKA/HHS Overlap ... & HHS and treated ... #differential #diagnosis ... #management #endocrinology
DKA vs HHS - Think of DKA and HHS on a spectrum of hyperglycemic emergencies -
DKA vs HHS - Think ... of DKA and HHS ... and starvation ketosis ... #endocrinology ... #comparison #diabetic
Hyperglycemic Crisis - Algorithm for DKA/HHS Diagnostic criteria for DKA: • pH < 7.3 • Anion gap
/HHS Diagnostic ... • Urine/serum ketones ... • Urine/serum ketones ... Algorithm #management #endocrinology ... #Diabetes #DM2
Pathyophysiology - hyperglycemic crises in patients with diabetes Key signs/symptoms of HHS/DKA: Both: Polyuria, polydipsia, weight loss,
Pathyophysiology ... patients with diabetes ... /DKA: Both: Polyuria ... Pathophys #EM #IM ... #Endo #DKA #HHS
Diabetic Ketoacidosis (DKA) - Pathogenesis and Clinical Findings • Note: in DKA, body K+ is lost
Diabetic Ketoacidosis ... ensure patient has ... #pathophysiology ... #endocrinology ... #diabetes
DKA DIAGNOSTIC CRITERIA: 1. Serum glucose >250 mg/dL 2. Arterial pH <7.3 3. Serum bicarbonate <18 mEq/L 4. At least
DKA DIAGNOSTIC CRITERIA ... patients with type 2 diabetes ... have new-onset diabetes ... previously established diabetes ... are Euglycemic Diabetic
There are similarities and differences between these 3 conditions which all carry treatment implications. Each mimic
conditions, serum BHB has ... In Starvation Ketosis ... drips unless also diabetic ... DKA is essentially ... #diagnosis #differential
Mycoses HISTOPLASMOSIS • Inhalation of conidia → Yeast → travel to lymph nodes → spread in body • Bird
antigen assay has ... MUCORMYCOSIS • Risk: Diabetes ... Mucormycosis has ... Aspergillosis Pathophysiology ... shock • Mortality rate
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