18 results
Pathophysiology of Diabetic Ketoacidosis (DKA) and Hyperglycemic Hyperosmolar Syndrome (HHS)
Absolute Insulin deficit:
 - Type I DM:
Pathophysiology ... of Diabetic Ketoacidosis ... #pathophysiology ... #comparison #endocrinology ... #ketoacidosis #
Ketosis Disorders - Comparison Table
 • Starvation Ketosis
 • Alcoholic Ketoacidosis (AKA)
 • Diabetic Ketoacidosis (DKA)
(AKA) • Diabetic ... Ketoacidosis (DKA ... ) • DKA/HHS Overlap ... #differential #diagnosis ... #management #endocrinology
Diabetes Insipidus vs Syndrome of Inappropriate ADH (SIADH) - Comparison Table

Diabetes Insipidus - Inadequate ADH
SIADH -
Diabetes Insipidus ... Excess ADH #Diabetes ... Comparison #Table #Pathophysiology ... #Signs #Symptoms ... #Diagnosis #Endocrinology
Pathyophysiology - hyperglycemic crises in patients with diabetes 
Key signs/symptoms of HHS/DKA:
Both: Polyuria, polydipsia, weight loss,
Pathyophysiology ... patients with diabetes ... Key signs/symptoms ... of HHS/DKA: Both ... Pathophys #EM #IM
DKA vs HHS
 - Think of DKA and HHS on a spectrum of hyperglycemic emergencies
 -
of DKA and HHS ... comparison #laboratory #diagnosis ... #endocrinology ... #comparison #diabetic ... #ketoacidosis #
Hyperglycemic Crisis - Algorithm for DKA/HHS

Diagnostic criteria for DKA:
 • pH < 7.3
 • Anion gap
Diagnostic criteria ... > 250 mg/dL Diagnostic ... Algorithm #management #endocrinology ... #Diabetes #DM2 ... #Ketoacidosis
Euglycemic Diabetic Ketoacidosis (EuDKA)
SGLT2 Inhibitors
Increasing Indications
Significant Adverse Drug Effects
Definition of EuDKA
 • Metabolic acidosis with pH
Euglycemic Diabetic ... Ketoacidosis (EuDKA ... level < 200 mg/dL Pathophysiology ... EuDKA #diagnosis ... #management #endocrinology
DKA DIAGNOSTIC CRITERIA:
1. Serum glucose >250 mg/dL
2. Arterial pH <7.3
3. Serum bicarbonate <18 mEq/L
4. At least
DKA DIAGNOSTIC CRITERIA ... Common, early signs ... several factors: the rate ... production, the rate ... closes and acidosis has
Diabetic Ketoacidosis (DKA) - Pathogenesis and Clinical Findings
 • Note: in DKA, body K+ is lost
Diabetic Ketoacidosis ... ensure patient has ... Signs/Symptoms/Complications ... DiabeticKetoacidosis #DKA #pathophysiology ... #endocrinology
Ketosis Disorders
Ketone bodies are a normal metabolic energy source. Excessive unregulated production of ketones, often accompanied
• Alcoholic ketoacidosis ... • Diabetic ketoacidosis ... of both DKA & HHS ... #differential #diagnosis ... #management #endocrinology