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management comparison diagnosis dka diabetic differential disorders hyperglycemic ketoacidosis ketones ketosis medications table anaphylaxis baqsimi ddxof diabeticketoacidosis dm2 dosing dpp4
Pathophysiology of Diabetic Ketoacidosis (DKA) and Hyperglycemic Hyperosmolar Syndrome (HHS) Absolute Insulin deficit: - Type I DM:
Pathophysiology ... Hyperglycemic Hyperosmolar ... Syndrome (HHS) ... #pathophysiology ... #comparison #endocrinology
Ketosis Disorders - Comparison Table • Starvation Ketosis • Alcoholic Ketoacidosis (AKA) • Diabetic Ketoacidosis (DKA)
Ketoacidosis (AKA) • Diabetic ... Hyperglycemic Hyperosmolar ... State (HHS) ... • DKA/HHS Overlap ... diagnosis #management #endocrinology
DKA vs HHS - Think of DKA and HHS on a spectrum of hyperglycemic emergencies -
DKA vs HHS - Think ... of DKA and HHS ... laboratory #diagnosis #endocrinology ... #comparison #diabetic ... #ketoacidosis #hyperosmolar
Mechanism of Action for Common Diabetes Medications • SGLT2i (Dapagliflozin) • TZD (Pioglitazone) • Biguanides (Metformin)
Action for Common Diabetes ... sarahthelyon #Diabetes ... #Medications #pharmacology ... #pathophysiology ... #endocrinology
Comparison of anti-diabetic or anti-hyperglycemic agents There are numerous anti-hyperglycemic agents available to manage Type 2 diabetes.
Comparison of anti-diabetic ... manage Type 2 diabetes ... of medications has ... #pharmacology #pharmacotherapy ... #endocrinology
Pathyophysiology - hyperglycemic crises in patients with diabetes Key signs/symptoms of HHS/DKA: Both: Polyuria, polydipsia, weight loss,
Pathyophysiology ... patients with diabetes ... signs/symptoms of HHS ... Pathophys #EM #IM ... #Endo #DKA #HHS
Ketosis Disorders Ketone bodies are a normal metabolic energy source. Excessive unregulated production of ketones, often accompanied
• Diabetic ketoacidosis ... Hyperglycemic hyperosmolar ... • DKA/HHS Overlap ... of both DKA & HHS ... diagnosis #management #endocrinology
Diabetic Ketoacidosis (DKA) - Pathogenesis and Clinical Findings • Note: in DKA, body K+ is lost
Diabetic Ketoacidosis ... ensure patient has ... DiabeticKetoacidosis #DKA #pathophysiology ... #endocrinology ... #diabetes
Anaphylaxis: Treatments (Acute) Additional Info: • IV steroids may be considered for prevention of late phase reactions.
prevention of late ... minimum of 4-6 hrs ... treatment) 1:1000 IM ... Treatments #Management #pathophysiology
DPP4 Inhibitors - Normal and Renal Dosing Increase Incretins (GLP-I & GIP) -> Stimulates Insulin, Inhibits Glucagon
post-prandial glucose and has ... This drug class has ... Renal #Dosing #Pharmacology ... #Management #Diabetes ... #DM2 #Endocrinology
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